Human MIRLET7E qPCR Primer Pair,即人MIRLET7E qPCR引物对,主要用于基于SYBR Green的qPCR、One-Step qRT-PCR或semi-quantitative PCR。本引物为预先设计、经过qPCR验证、预混的引物对。 qPCR (Quantitative PCR)即定量PCR,也称实时荧光定量PCR或实时定量PCR (Real-time quantitative PCR)、实时PCR (Real-time PCR...
血浆miR--320、miR--let--7e及miR--21作为视网膜母细胞瘤早期诊断标志物的研究
Although miR-let-7e has been implicated in several types of cancer regulation, relatively little is known about the function of miR-let-7e in PTC. In this study, we showed that the overexpression of miR-let-7e or knockdown of high mobility group box 1 (HMGB1) inhibited cell migration and...
专利摘要:本发明公开了miR‑125a‑5plet‑7e‑5p拮抗剂治疗非酒精性脂肪肝病的应用。本发明通过实验证实,miR‑125a‑5p和let‑7e‑5p共同靶向PRKAA2基因通过AMPK途径促进非酒精性脂肪肝病进展,而miR‑125a‑5plet‑7e‑5p拮抗剂可以减缓非酒精性脂肪肝病进展,在治疗非酒精性脂肪肝病中具有很好的...
Operating characteristic (ROC) curve for Let-7e and the combination with miR-126.Operating characteristic (ROC) curve for Let-7e and the combination with miR-126.Bernardo, J. KrauseIvo, CarrascoWongAngélica, DominguezPilar, ArnaizMarcelo, FaríasSales...
Convergence of Let-7e and miR-126-regulated signalling pathways at protein level.Bernardo J. KrauseIvo CarrascoWongAngélica DominguezPilar ArnaizMarcelo FaríasSalesa BarjaFrancisco MardonesPaola Casanello
结果非DR患者相比,PDR和NPDR患者的血浆miR-let-7e-5p表达水平降低,LncRNA NEAT1表达水平增加(P<0.05);并且与NPDR组相比,PDR组的血浆miR-let-7e-5p表达水平降低,LncRNA NEAT1表达水平升高(P<0.05);DR患者血浆miR-let-7e-5p与LncRNA NEAT1呈负相关(r=-0.534,P<0.05);miR-let-7e-5p诊断DR的AUC为0.856(...
本发明公开一种miR Let7e和/或miR20a在制备诊断慢加急肝衰竭的产品中的应用,属于生物医学技术领域.本发明首次发现了miRNA Let7e和/或miRNA20a表达水平与慢加急肝衰竭的发生发展相关,通过检测受试者miRNA Let7e和/或miRNA20a的表达水平,可以判断受试者是否患有慢加急肝衰竭或者判断受试者是否存在患有慢加急肝衰竭的...
目的:本文通过实时定量PCR(real-time PCR,RT-PCR)方法检测候选miRNA分子(miR-373,miR-503,miR-320,miR-let-7e,miR-492,miR-498和miR-21)在视网膜母细胞瘤(RB)患者和健康对照者血浆样本中的表达水平,验证并获得在RB血浆中表达异常的miRNA,探讨其与RB患者临床特征之间的关系,并分析其作为RB早期诊断分子标志物的...
变应性鼻炎患者血清miR-Let-7e,sCD48水平变化 及其与病情的关doi:10.3969/j.issn.1002-266X.2023.35.017栾镐彤李琦Shandong Medical Journal