细胞在正常培养基中培养48 h,转染阴性对照的miR-665模拟物,然后Dex预处理,然后H/R处理;(C) Dex+HR+miR-665mim,细胞在正常培养液中培养48 h,转染miR-665模拟物,上调miR-665表达水平,然后Dex预处理,之后进行H/R处理;(D) Dex+H...
miR-665 Targeting BCL2L11 Regulates the Myoblasts Proliferation of Wu’an Goat FENG Jing, SHENG Hui, ZHANG Xiaosheng, GUO Xiaofei, YAO Dawei, LI Yupeng, CHEN Longbin, ZHANG Jinlong 畜牧兽医学报 . 2025, (2): 582 -590 . DOI: 10.11843/j.issn.0366-6964.2025.02.010 ...
综上所述,在山羊背最长肌组织中miR-665作为BCL2L11的调控元件,能够显著抑制山羊成肌细胞中BCL2L11的表达水平,当miR-665过表达后,能够促进成肌细胞的增殖情况。 关键词: miR-665, BCL2L11, 肌肉, 武安山羊, 成肌细胞 Abstract: This study aimed to use molecular biological methods to explore the effect ...
Circ-0000953可能通过miR-665-3pAtg4b轴靶向调控，加重糖尿病肾病足细胞损伤。影响肾功能 Circ-0000953可能影响肾功能，导致糖尿病肾病病情恶化。02 miR-665-3p与糖尿病肾病 miR-665-3p的生物功能 调节细胞生长与分 化 miR-665-3p在某些情况下可以作为癌基因或抑癌基因，通过调节细胞生长与分化来影响肿瘤的发展。参...
miR-665 and miR-4732-5p (Figure 4A,G) were significantly higher in RIF compared to the control. Additionally, the expressions ofNRXN3,BVES,PLA2G4A,AHCYL2, andMICA(Figure 4B–F), putative target genes of miR-665, andPRKXandCNKSR3(Figure 4H,I), putative target genes of miR-4732-5p, ...
density, then further impaired cardiac function in vivo. Furthermore, CD34 was confirmed as one of the miR-665 targets. Consistently, re-expression of CD34 attenuated miR-665-mediated damage effects in vitro and in vivo. We also found that Sp1 regulated miR-665 expression in endothelial cells....
To evaluate miR-665, miR-4732-5p, and miR-375 expression, real-time RT-PCR was used. RNA (500 ng) was used for RT-PCR reactions that were performed using an miScript II RT kit (Qiagen, Hilden, Germany) according to the manufacturer’s protocol. Thaw all RNA on ice. Thaw 10× mi...
pEGP-mmu-mir-665 Expression Vector 英文名称: miRNASelect? pEGP-mmu-mir-665 Expression Vector 总访问: 216 国产/进口: 进口 半年访问: 17 产地/品牌: 美国Cell Biolabs 产品类别: 细胞生物学试剂 规格: MMU-MIR-665 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
MiR-665调控STAT3/IL-17环路对自身免疫性葡萄膜炎的作用研究项目 核心参数要求:商品类目: 荧光定量PCR; 服务内容及要求:MiR-665调控STAT3/IL-17环路对自身免疫性葡萄膜炎的作用研究项目;采购人需求描述:MiR-665调控STAT3/IL-17环路对自身免疫性葡萄膜炎的作用研究徐完全满足采购需求。;次要参数要求: 1项 100000.00...
Although numerous miRNAs have been discovered, their functions in the different subcellular organelles have remained obscure. In this study, we found that miR-665 was enriched in the nucleus of cardiomyocytes, and then investigated the underlying role of