miR-515-5p抑制剂组、miR-515-5p抑制剂阴性对照(negative control, NC)组,CCK-8法检测细胞增殖情况;划痕愈合和Transwell实验分别评估细胞迁移、侵袭能力;双荧光素酶报告基因检测miR-515-5p和ITLN2的靶向关系;RT-qPCR技术检测各组细胞...
双荧光素酶报告基因实验证实,TRIM31是miR-515-5p靶基因.过表达miR-515-5p可明显上调HT-29细胞中miR-515-5p表达水平,抑制细胞增殖,迁移和侵袭能力,并下调TRIM31 mRNA及TRIM31,PI3K和p-AKT蛋白表达水平(P<0.01).而过表达TRIM31可显著上调HT-29细胞中TRIM31 mRNA和蛋白表达,促进细胞增殖,迁移和侵袭,并上调PI3K...
MCE 国际站:hsa-miR-515-5p antagomir 产品活性:hsa-miR-515-5p antagomir 是一种经过特殊化学修饰的成熟miRNA的互补单链,全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA antagomir通过特异性结合成熟miRNA,阻止miRNA与其靶基因的互补配对,从而抑制miRNA...
ppy-miR-515-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:ppy-miR-515-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:ppy-miR-515-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
MiR-515-5p acts as a tumor suppressor via targeting TRIP13 inprostate cancerXiyan Zhanga , Jian Zhou b , Dongwei Xue c , Zhi Li d , Yili Liu c , Liming Dong c, ⁎aDepartment of General Surgery, The Fourth Aff i liated Hospital of China Medical University, Liaoning 110000, Shenyang...
双荧光素酶报告基因实验证实,TRIM31是miR-515-5p靶基因.过表达miR-515-5p可明显上调HT-29细胞中miR-515-5p表达水平,抑制细胞增殖,迁移和侵袭能力,并下调TRIM31 mRNA及TRIM31,PI3K和p-AKT蛋白表达水平(P<0.01).而过表达TRIM31可显著上调HT-29细胞中TRIM31 mRNA和蛋白表达,促进细胞增殖,迁移和侵袭,并上调PI3K...
展开更多 Objective To explore the expression levels and clinical significance of serum long noncoding RNA myocardial infarction associated transcript(lncRNA MIAT)and microRNA-515-5p(miR-515-5p)in elderly patients with chronic obstructive pulmonary disease(COPD)at different perio...MORE 作者 丁静 杨...
miR-515-5p was measured after the knockdown of LINC00673 by using qRT-PCR in MDA-MB-231 and MDA-MB-453 cells.eExpression of LINC00673 in miR-515-5p mimics or inhibitor transfected MDA-MB-231 and MDA-MB-453 cells, as determined by qRT-PCR.f-gElevation and depression of miR-515-5p ...
LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway 来自 掌桥科研 喜欢 0 阅读量: 178 作者:K Qiao,S Ning,L Wan,H Wu,Q Wang,X Zhang,S Xu,D Pang
Journal of Experimental & Clinical Cancer Research https://doi.org/10.1186/s13046-019-1421-7 (2019) 38:418 RESEARCH Open Access LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway Kun Qiao1, Shipeng Ning1, ...