Our results demonstrated that the DC-derived exosomes can inhibit Th9 cell differentiation through miR-493-5p, thus DC-derived exosomal miR-493-5p/FOXO1/Th9 may serve as a potential therapeutic target in the development of asthma.doi:10.1186/s12931-022-02207-2Rao, Xingyu...
MCE 国际站:hsa-miR-493-5p antagomir 产品活性:hsa-miR-493-5p antagomir 是一种经过特殊化学修饰的成熟miRNA的互补单链,全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA antagomir通过特异性结合成熟miRNA,阻止miRNA与其靶基因的互补配对,从而抑制miRNA...
在Ⅰ～Ⅱ期PHC患者血清中miR-142-3p、miR-493-5p表达水平显著低于Ⅲ期和Ⅳ期,分期越高其表达水平越低,进一步证实了血清miR-142-3p、miR-493-5p水平变化与PHC患者病情密切相关。通过ROC曲线分析发现,血清miR-142-3p和miR-493-...
货号:oar-miR-493-5p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:oar-miR-493-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
双荧光素酶报告实验检测miR-493-5p和GIT1的靶向关系.结果 A2780、SKOV3和OVCAR3细胞中miR-493-5p低表达,GIT1高表达(P<0.05);过表达miR-493-5p后,SKOV3细胞增殖活性、迁移和侵袭数降低(P<0.05).miR-493-5p靶向调控GIT1的表达,过表达GIT1降低了miR-493-5p对SKOV3细胞增殖、迁移和侵袭的抑制作用以及对p-...
Purpose: To investigate the effect of miR-493-5p in lipopolysaccharide (LPS) -induced ATDC5 chondrogenic cells. Methods: The MTT assay was used to determine the viability of LPS-induced ATDC5 cells. ENCORI (starbase.sysu.edu.cn/) was used to predict the target of miR-493-5p. Quantitative...
miR-493-5p,CHE联合GP73检测在肝癌筛查,病情评估中的应用研究 目的 探讨miR-493-5p,胆碱脂酶(CHE)联合高尔基体糖蛋白73(GP73)检测在肝癌筛查,病情评估中的应用价值.方法 选取2015年7月～2019年7月安阳市第五人民医院收治的98例肝... 李俊娜,韩晓亮,谢东文,... - 《承德医学院学报》 被引量: 0发表: 202...
The miR-493-5p/FUT4 pathway has therapeutic potential in breast cancer. 展开 关键词: FUT4 breast cancer miR-493-5p breast cancer cell lines invasion tumorigenicity DOI: 10.3892/or.2016.4882 被引量: 9 年份: 2016 收藏 引用 批量引用 报错 分享 ...
The miR-493-5p/FUT4 pathway has therapeutic potential in breast cancer.Introduction Breast cancer is the most common invasive cancer and the second cause of cancer-related death in women (1,2). Each year more than a half a million new cases of breast cancer are diagnosed in the US and ...
miR-493-5p suppresses hepatocellular carcinoma cell proliferation through targeting GP73 Biomedicine & Pharmacotherapy Volume 90, June 2017, Pages 744-751 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and personalFor academic or personal use only. CliniciansFor ...