在Ⅰ～Ⅱ期PHC患者血清中miR-142-3p、miR-493-5p表达水平显著低于Ⅲ期和Ⅳ期,分期越高其表达水平越低,进一步证实了血清miR-142-3p、miR-493-5p水平变化与PHC患者病情密切相关。通过ROC曲线分析发现,血清miR-142-3p和miR-493-...
目的:探讨在反式-7,8-二羟-9,10-环氧苯并芘(anti-BPDE)诱导转化的人支气管上皮细胞(16HBE-T)中低表达的mir-493 -5p在化学致癌物致癌过程中的作用.方法:运用实时荧光定量PCR(qRT-PCR)验- miR-493-5p成熟体在16HBE-T和非转化对照细胞(16HBE-N)的表达水平.瞬时转染miRNA的模拟物,改变16HBE-T中miR-493...
在Ⅰ～Ⅱ期PHC患者血清中miR-142-3p、miR-493-5p表达水平显著低于Ⅲ期和Ⅳ期,分期越高其表达水平越低,进一步证实了血清miR-142-3p、miR-493-5p水平变化与PHC患者病情密切相关。通过ROC曲线分析发现,血清miR-142-3p和miR-493-...
To determine whether FUT4 expression is indeed regulated by miR-493-5pin vitro, the MDA-MB-231 cells were transfected with miR-493-5p agomir, while the MCF-7 cells were transfected with the miR-493-5p antagomir. As expected, miR-493-5p agomir-treated cells showed higher expression of miR...
货号:oar-miR-493-5p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:oar-miR-493-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
E2F3 was confirmed as a target of miR-493-5p, and the effects of miR-493-5p on the phenotype of glioma cells could be partly reversed by E2F3. Besides, it was also found that miR-493-5p could effectively suppress the expression of E2F3 and then improve the dysfunctions of the P53 and...
miR-493-5p suppresses hepatocellular carcinoma cell proliferation through targeting GP73 Biomedicine & Pharmacotherapy Volume 90,June 2017, Pages 744-751 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and personalFor academic or personal use only. ...
Purpose: To investigate the effect of miR-493-5p in lipopolysaccharide (LPS) -induced ATDC5 chondrogenic cells. Methods: The MTT assay was used to determine the viability of LPS-induced ATDC5 cells. ENCORI (starbase.sysu.edu.cn/) was used to predict the target of miR-493-5p. Quantitative...
Taken together, our data suggest that FUT4 may have a potential role in the treatment of breast cancer, as well as miR-493-5p is a novel regulator of invasiveness and tumorigenicity of breast cancer cells through targeting FUT4. The miR-493-5p/FUT4 pathway has therapeutic potential in ...
In addition, NR2F1-AS1 was found to be a sponge of miR-493-5p, and MAP3K2 was a downstream gene of miR-493-5p. Moreover, the expression of MAP3K2 was notably reduced by miR-493-5p, and NR2F1-AS1 counteracted the inhibition of miR-493-5p. Conclusion. Thus, NR2F1-AS1 was ...