微小RNA-490 (miR-490)是miRNA家族中重要的一员,其与肿瘤的发生、发展密切相关。研究表明miR-490在胃癌、结直肠癌、乳腺癌等多种肿瘤中异常表达,并在不同肿瘤细胞的增殖、凋亡、侵袭、转移等生物学行为中扮演着癌基因或抑癌基因的角色。miR-490有望作为肿瘤诊断和临床预后的指标,对其机制的深入研究有望为肿瘤诊治...
Transwell, and xenograft experiments were employed to evaluateLUAD cell proliferation, migration, and tumor growth, respectively. T h e relationship between miR-490-3pand lncRNA NEAT1 was analyzed using a luciferase reporter assay. Results. Herein, we found that miR-490-3p expression...
ITGB1 mRNA水平较低(均P<0.05);与Dex低剂量组比较,Dex中剂量组、Dex高剂量组、Dex高剂量+inhibitor NC组HCC‑827细胞miR‑490‑3p水平较高,ITGB1 mRNA水平较低(均P<0.05);与Dex中剂量组比较,Dex高剂量组、Dex高剂量+inhib...
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mml-miR-490-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:mml-miR-490-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:mml-miR-490-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
miR-490 suppresses telomere maintenance program and associated hallmarks in glioblastoma Cellular and molecular life sciences : CMLS (2021) - 2 Comments doi: 10.1007/s00018-020-03644-2 issn: 1420-682x issn: 1420-9071 pubmed: 32970185
全氟辛酸(PFOA)鸡胚发育暴露的长期毒性研究及PPARα作用 目的:全氟辛酸(PFOA)具有发育毒性,但是PFOA发育暴露后的长期健康效应研究较少,故本研究采用鸡胚模型研究阐明胚胎时期PFOA发育暴露所致的长期健康效应,并进一步深入揭... 倪皓 - 《青岛大学》 被引量: 0发表: 2023年 六氟环氧丙烷寡聚物(HFPO oligomers)发育...
We also found that overexpression of miR-490-3p led to an increase in cell proliferation, migration, and invasion abilities and that it contributed to EMT. The inhibition of miR-490-3p had the opposite effect on the cells. We identified ERGIC3 (endoplasmic reticulum-Golgi intermediate ...
These results indicated that miR-490-3p functions as a tumor suppressor in CRC, and may be a novel potential diagnostic and prognostic biomarker for CRC. 展开 关键词: colorectal cancer miR-490-3p VDAC1 biomarker.DOI: 10.7150/jca.23662 被引量: 7 ...
8:561678.doi: 10.3389/fmolb.2021.561678MiR-490-3p Silences CDK1 andInhibits the Proliferation of ColonCancer Through an LLPS-DependentmiRISC SystemDa Qin, Rui Wei, Shengtao Zhu, Li Min * and Shutian Zhang *Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Department of ...