MicroRNA-452-5p (miR-452-5p) and Moesin (MSN) have been proved to be related with regulation of tumors. If miR-452-5p could regulate NSCLC through targeting MSN remain unclear. Methods: TargetScan data and GEPIA databases were used to predict binding site and analyze gene exp...
mml-miR-452-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:mml-miR-452-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:mml-miR-452-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
CircZNF652 promotes the goblet cell metaplasia by targeting the miR-452-5p/JAK2 signaling pathway in allergic airway epithelia 环状RNA在多种人类疾病中发挥着重要潜在作用,但它们在哮喘杯状细胞化生中的作用尚不清楚。Wang等分享...
水平.2.miR-452-5p促进结直肠癌细胞恶性生物学行为1)体外增殖:将miR-452-5p mimics和inhibitors瞬时转染至结直肠癌细胞中,验证效率后进行CCK8实验及平板克隆实验;2)细胞周期:通过细胞周期实验验证miR-452-5p对结直肠癌细胞周期的影响;3)化疗抵抗:通过IC50,细胞凋亡实验及western Blot实验验证miR-452-5p对结直...
Role of miR-452-5p in the tumorigenesis of prostate cancer: A study based on the Cancer Genome Atl(TCGA), Gene Expression Omnibus (GEO), and bioinformatics... Role of miR-452-5p in the tumorigenesis of prostate cancer: A study based on the Cancer Genome Atl (TCGA), Gene Expression ...
项目简介 项目名称 肾癌细胞与肥大细胞间“对话”诱导舒尼替尼耐药:基于IL33介导的miR-452-5p相关外泌体的研究 学科学类 H1619 医学科学部_肿瘤学_泌尿系统肿瘤 项目批准号 81972393 资助类型 面上项目 资助经费 55万元 项目负责人 郑军华 职称 暂无
KYSE-150细胞miR-452-5pSRY盒转录因子7Wnt/β-catenin信号通路目的:检测miR-452-5p在食管鳞状细胞癌(ESCC)中的表达,并探讨其异常表达对食管癌KYSE-150细胞增殖,侵袭能力和EMT进程的影响及其分子机制.方法:收集2012年3月至2015年12月在河北医科大学第四医院就诊的86名ESCC患者的癌组织样本和对应的癌旁组织,用qPCR...
乳腺癌细胞中miR-452-5p表达显著降低,SOX5表达显著升高(P<0.05);过表达miR-452-5p后乳腺癌SKBR-3细胞活性显著降低,侵袭和转移能力减弱,Cyclin D1,CDK4,MMP-2,MMP-9蛋白表达水平显著降低(P<0.05);双荧光素酶实验显示miR-452-5p可靶向调控SOX5.与miR-452-5p+pcDNA组比较,miR-452-5p+pcDNA-SOX5组SKBR-3...
We confirmed decreased expression of hsa-miR-452-5p when either RELA or RELB were depleted and increased expression of hsa-miR-335-5p when RELA was depleted. Either inhibiting miR-452-5p or mimicking miR-335-5p functionally decreased the stem-like potential of the TICs. These results high...
MiR‐452‐5p functions in RB were evaluated via Cell Counting Kit‐8, 5‐Ethynyl‐2′‐deoxyuridine assay, flow cytometry, Western blot, and Transwell. MiR‐452‐5p mechanism in RB was assessed using bioinformatics software Starbase and dual‐luciferase reporter gene assay. Meanwhile, miR‐452‐...