miR-425-5pMALAT1TUG1The Wnt/beta-catenin signaling pathwayOsteosarcomaMultiple miRNAs have been recognized as critical regulators in osteosarcoma (OS) carcinogenesis. miR-425-5p was demonstrated to be downregulated in the serum of OS patients. Howeve... 查看全部>>Guohui Yang aChi Zhang bNan Wang aJuwu Chen aThe Inter...
A:Promo软件预测miR-425-5p基因启动子区域中3个潜在的NF-κB结合位点(-1 720、-1 316和-138 bp);B:双荧光素酶报告基因检测含有不同结合位点的miR-425-5p启动子活性;C:染色质免疫共沉淀检测NF-κB与miR-425-5p基因启动子结合位点1的结合...
一、不同浓度脂多糖对肠道L细胞的细胞活力、GLP-1分泌及miR-425-5p表达的影响随着脂多糖浓度的升高,细胞凋亡增加(P<0.01,图1A),细胞活力下降(P<0.01,图1B),活性GLP-1水平降低(P<0.01,图1C),miR-425-5p表达增加(P<0.01,...
摘要：目的分析晚期结直肠癌患者血清miR-143-3p 、miR-425-5p 表达水平及其与化疗敏感性、预后的关系。方法选取2017年1月1日至2018年12月10日我院肿瘤内科收治的82例晚期结直肠癌患者作为观察组，另选取同期我院70名体检健康人群作为对照组。均行血清miR-143-3p 、miR-425-5p 表达水平测定。比较两组的血清miR-...
miR-425-5pHBZY 1 CellsTGF betaP65SitagliptinObjective : Sitagliptin (Sitagtin) is widely involved in the treating process for several diseases in humans, covering DN (Diabetic Nephropathy). In the present research, the aim was at examining the roles of the miR-425-5p/TGFβ /P65 pathway in ...
www.nature.com/cddiscovery ARTICLE OPEN MCT4-driven CAF-mediated metabolic reprogramming in breast cancer microenvironment is a vulnerability targetable by miR-425-5p Alessandra Affinito1,2, Cristina Quintavalle3, Rosario Vincenzo Chianese1, Giuseppina Roscigno1, Danilo Fiore1,3, Valeria D'Argenio 4...
Liver damage, RIP1-mediated necroptosis, IL-1β, and TNF-α were suppressed by miR-425-5p agomiR, but further aggravated by miR-425-5p antagomiR. Furthermore, we demonstrated miR-425-5p targeted the 3′UTR of RIP1 mRNA to inhibit RIP1 expression and activated RIP1 reversed miR-425-5p...
英文别名: hsa-miR-425-5p miRNA Antagomir 中文名: 中文别名: CBNumber: CB017299741 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 hsa-miR-425-5p miRNA Antagomir化学性质 安全信息hsa-miR-425-5p miRNA Antagomir性质、用途与生产工艺 hsa-miR-425-5p miRNA Antagomir ...
目的 分析经阴道彩色多普勒超声联合血清miR-130a,miR-425-5p水平检测对宫颈癌的诊断效能.方法 选取2017年1月～2019年1月在郑州市第七人民医院诊治的宫颈癌患者58例和宫颈炎及宫颈上皮瘤变者77例分别为癌症组和疾病组,60例同期来院体检结果正常的健康女性为对照组.对三组实施经阴道彩色多普勒超声检查,... 查看全...
Conclusions: The results of our study suggest the possible involvement of miR-148a-3p, miR-425-3p, and miR-20a-5p in the pathogenesis of IgA nephropathy. Keywords: microRNAs; IgA nephropathy; kidney 1. Introduction IgA nephropathy (IgAN) is the most common primary proliferative glomerulonephritis...