细胞增殖凋亡迁移侵袭目的探讨miR-365-3p对骨关节软骨细胞增殖,凋亡,迁移和侵袭影响及作用机制.方法以正常人软骨组织为对照,qRT-聚合酶链反应(PCR)检测骨关节炎患者软骨组织中miR-365-3p表达水平.分离培养骨关节软骨细胞,分别转染miR-365-3p模拟物(miR-365-3p组)和模拟对照(miR-NC组)后,四甲基偶氮唑蓝(MTT)和...
cgr-miR-365-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:cgr-miR-365-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:cgr-miR-365-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
货号:gga-miR-365-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:gga-miR-365-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
MiR-365a-3p mimic Cell cycle ROS Exosome HepG2 Nrf2 HEK293 1. Introduction Hepatocellular carcinoma (HCC) is defined as a multi-stage malignancy of the liver [1] and ranked as the fifth most common and second most lethal cancer amongst all [2]. A recent transcriptome profiling study has...
RNA pulldown assay and dual-luciferase reporter assay confirmed thatmodulated the expression of NRF2 via stabilizing miR-365a-3p. As low solubility of erastin limits its efficient application, we further prepared folate (FA)-modified liposome (FA-LP) nanoparticles for targeted co-delivery of ...
外周血miR-29a-3p、miR-365a-3p在活动性肺结核和结核潜伏感染者中的表达
本研究主要探讨Dex调控微RNA(miRNA)‑490‑3p(miR‑490‑3p)/整合素β1(ITGB1)轴对非小细胞肺癌(NSCLC)增殖、迁移和侵袭的影响,为临床用药提供参考。 1 材料与方法 1.1 实验材料及分组 于37 °C、5%CO2的环境中用RPMI 16...
细胞凋亡目的 探讨miR-365-3p通过周期素依赖性激酶-10(CDK-10)影响口腔鳞癌(OSCC)细胞增殖,凋亡与周期的机制.方法 收集在本院就诊的40例口腔鳞癌患者肿瘤组织样本及癌旁正常组织样本,检测其miR-365-3p和CDK-10表达水平.随机将人舌鳞癌细胞系(CAL-27)分为空白组,对照组及miR-365-3p三组.对照组与miR-365-3p...
miR-365-3pCPT1AFatty acid oxidationProliferationMigrationThe relationship between abnormal lipid acid metabolism and the progression of lung cancer is increasingly evident. Carnitine palmitoyltransferase 1A (CPT1A), a rate-limiting enzyme in fatty acid oxidation, has been implicated in the advancement of...
miR-365-3p, whose expression was significantly downregulated upon IL-17 stimulation, was demonstrated to exert remarkable anti-inflammatory effect to decrease IL-17-provoked inflammatory cytokines (KC/IL-8 and IL-6) in both airway epithelial cells and macrophages of murine...