来自温州医科大学附属第一医院的王均炉团队最新研究发现,缺血性脑卒中患者血浆和MCAO大鼠大脑皮质中miR-324-3p含量降低,miR-324-3p agomir可增加大鼠脑梗死体积,加重神经功能缺损。为进一步探讨其作用机制,开展的体外实验OGD/REP细胞模型中发现,miR-324-...
miR-324-3 p 通过调控 MC1R 基因 影响黑色素的形成 曾庆宝,范瑞文,张秋月,郝晓娟,武良琦,任玉红 * (山西农业大学动物科技学院,太谷030801 ) 摘 要:旨在证明miR-324-3p 可以通过调控其预测的靶基因MC1R及其下游基因的表达从而对羊驼皮肤黑色素 的合成产生影响。本研究在体外培养的羊驼皮肤黑色素细胞中转染miR-32...
结果显示:(1)miR-324-3p在棕色与白色羊驼皮肤中均有表达,且在棕色羊驼皮肤中极显著表达(P<0.01),其相对表达量是白色的1.64倍;(2)黑色素细胞被转染了miR-324-3p过表达载体后,处理组靶基因MC1R及其下游调控基因Mitf,Tyr和Tyrp2的表达量与黑色素产量较空白对照组均有下调,且以Mitf基因表达量极显著下调(P<0.01...
Objective To investigate the effect of miR-324-3p on the migration and invasion in nasopharyngeal carcinoma( NPC) in vitro. Methods MiR-324-3p mimic was used to up-regulate the expression of miR-324-3p in NPC 5-8F and 6-10B cell lines,and then alterations of migration and invasion were...
(均P<0.05).miR-133a-3p,miR-324-3p二者联合预测持续性心房颤动患者射频消融术后房颤复发的AUC为0.901,敏感度和特异度分别为82.81%,86.21%,优于各自单独预测(Z=4.210,2.804,均P<0.05).结论 持续性心房颤动患者血清miR-133a-3p,miR-324-3p表达显著降低,二者联合对预测持续性心房颤动患者射频消融术后房颤...
持续性心房颤动患者血清 miR-133a-3p 和 miR-324-3p 表达与射频消融术后房颤复发的关系 doi:10.3969/j.issn.1671-7414.2024.06.018Journal of Modern Laboratory Medicine王岳胜刘晓晨刘恩香李晶晶
货号:cgr-miR-324-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:cgr-miR-324-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
miR-324-3p and SMAD4; enzyme-linked immunosorbent assay (ELISA) to determine the levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST); and cell counting kit-8 (CCK-8) and flow cytometry to evaluate the effects of miR-324-3p on cell proliferation and cycle/...
Moreover, our findings presented miR-508-5p to behave as a promising relapsed indicator in childhood ALL which can be applied in the development of novel therapeutic strategies. 展开 关键词: Childhood acute lymphoblastic leukemia ABCA3 transporter Multidrug resistance miR-324-3p miR-508-5p ...
BioTNT chi-miR-324-3p qPCR试剂盒 产品中心 >> 试剂 >> 分子生物学试剂 >> microRNA qPCR Kits关 闭 分类:microRNA qPCR Kits 品牌:BioTNT 货号:chi-miR-324-3p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:chi-miR-324-3p 特异性茎环引物试剂盒 ￥615 ...