miR-302dTle4双荧光素酶报告检测试验旨在探究精原干细胞(SSCs)形成过程中的关键miR-302d行使功能的分子机制.试验克隆mi R-302d前体序列并连入PGMLV-CMV-MCS-EF1-Zs Green1-T2A-Puro构建mi R-302d过表达载体(mi R-302d mimics);合成mi R-302d的干扰靶点并连入PGMLV-SC5载体构建mi R-302d干扰载体(mi R...
bta-miR-302d qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:bta-miR-302d 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:bta-miR-302d 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶...
hsa-miR-302d-5p mimic CAS No. : MCE 国际站:hsa-miR-302d-5p mimic 产品活性:hsa-miR-302d-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA 相关产品:hsa-miR-4728-3p agomir | hsa-miR-126...
货号:gga-miR-302d 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:gga-miR-302d 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物...
货号:ocu-miR-302d-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:ocu-miR-302d-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制...
We experimentally demonstrated that miR-302 cluster, including miR-302a, miR-302b, miR-302c and miR-302d exert a combinatorial effect on the reverse the drug resistance of breast cancer cells. The four miR- NAs cooperatively downregulate P-glycoprotein (P-gp)ex- pression in regulating drug ...
MIR-302a/b/c/d cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein(P-gp) by targeting MAP/ERK kinase kinase 1 (MEKK1) The importance of individual microRNAs (miRNAs) in tumor has been established in different cancers. However, their association with tumor ...
The miR-302S family including miR-302a, miR-302b, miR-302c, and miR-302d was significantly down-regulated in P-glycoprotein (P-gp)-overexpressing MCF-7/ADR cells. Overexpression of miR-302 increased intracellular accumulation of ADR and sensitized breast cancer cells to ADR. Most importantly...
miR-302/367 gene cluster. The MEKK1 band in Fig. 6b is not our malicious cut picture. Our original bands are shown in the following figure, The groups included include blank control, negative control, mir-302a, mir-302b, mir-302c, miR-302d, miR-367, miR-302/367 cluster and miR-...
Similar to SH-SY5Y, long-term exposure to ethanol induced miR-497 and miR-302b in IMR-32, another human neuroblastoma cell line. Using in silico approaches, BCL2 and cyclin D2 (CCND2) were identified as probable target genes of these miRNAs. Cotransfection studies with 3′-UTR of these...