为了观察miR-2861在细胞水平上的作用,我们从慢病毒转染的Treg细胞模型中提取外泌体(miR-NCKD-Exos, miR-2861KD-Exos, miR-NCOE-Exos和miR-2861OE-Exos),并将外泌体与OGD/ R处理的bEnd. 3细胞共培养。我们发现miR-2861在miR-2861KD-Exos组中的表达明显低于miR-NCKD-Exos组。此外,miR-2861在miR-2861OE-E...
图4 过表达miR-2861 对HG诱导的MC损伤、ECM集聚的影响 流式细胞检测显示,miR-2861过表达显著减轻了HG诱导的SV40-MES-13细胞G1期阻滞(4A,4B);[35S]-甲硫氨酸标记蛋白质合成实验表明,miR-2861过表达显著减少了HG诱导的细胞新蛋白合成(P<0.001)(4C)。蛋白免疫印迹检测显示,miR-2861过表达显着抑制 HG 诱导的 ...
ppy-miR-2861 qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:ppy-miR-2861 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:ppy-miR-2861 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶...
M, Zimmermann J, Handrick R, Hesse F, et al: miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality. ... - 《Biotechnology & Bioengineering》 被引量: 0发表: 2015年 EFFECTIVE MICRO-RNAS FOR CELL LINE ENGINEERING AND CELLULAR MECHANISMS OF ACTIO...
mmu-miR-2861 agomir CAS No. : MCE 国际站:mmu-miR-2861 agomir 产品活性:mmu-miR-2861 agomir 是一种经过特殊化学修饰的miRNA模拟物,miRNA成熟链全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性miRNA,上调miRNA活性。与普通...
目的研究狼疮性肾炎患者血清miR-2861和miR-4532表达水平及临床意义.方法回顾性分析2015年7月至2017年12月住院的89例狼疮性肾炎(LN)患者血常规等临床资料,其中活动期48例,稳定期41例,另选同时期体检健康者45例作为对照组.检测受试者血清miR-2861,miR-4532,白介素6(IL-6),白介素10(IL-10)水平及肾小球滤过率...
We showed that miR-2861 was downregulated in cervical cancer tissues and negatively correlated with advanced tumor stage and lymph node metastasis. Overexpression of miR-2861 suppressed cervical cancer cell proliferation and invasion and enhanced apoptosis. Subsequent investigation revealed that EGFR, AKT2...
MiR-2861 expression was significant higher in LCSCs no matter compared to the differentiation cells or normal cells. HDAC5 expression was positively correlated with miR-2861 in LCSCs and knockdown of miR-2861 decreased the expression of HDAC5, which implied that HDAC5 may be involved in the ...
hsa-miR-2861 mimic 产品活性:hsa-miR-2861 mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 产品来源: https://www.medchemexpress.cn/hsa-mir-2861-mimic.html 研究领域:Epigenetics 作用靶点:MicroRNA In Vitro: 1. miRNA Resuspension 1.1 Brief...