综上所述,该研究发现了轻度 COVID-19 患者血清中 miRNA 的独特表达模式。miR-27a-5p 的高表达可能对重症疾病具有保护作用;miR-1246 的下调与有效的抗病毒细胞宿主防御相关;miR-21-5p 表达降低可能预防肺纤维化的发展;miR-423-5p 有望成为 SARS-CoV-2 感染早期的生物标志物。 然而,该研究也存在一定局限性,如...
Visceral adipocyte–derived extracellular vesicles and their cargo miR-27a-5p lead to β-cell insulin secretion injury and glucose intolerance by targeting L-type Ca2+ channel subtype CaV1.2. Blockage of visceral adipocyte extracellular vesicle miR-27a-5p expression improves β-cell insulin secretion ...
miR-27a-5pTraf3inflammatory injuryceruleinacute pancreatitisAcute pancreatitis (AP), a sudden inflammatory process of pancreas, is painful and may contribute to death. The aberrant expression of miR-27a-5p has been reported in many types of cancers and diseases including AP. Thus, it is urgent ...
货号:bta-miR-27a-5p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:bta-miR-27a-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
货号:cgr-miR-27a-5p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:cgr-miR-27a-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
摘要: METTL3 and FAM230B are high-expressed in gastric cancerMETTL3 binds to FAM230B and up-regulates its m6A modification, therefore increases FAM230B stabilityFAM230B inhibits GC cells ferroptosis by regulating miR-27a-5p/BTF3关键词:
miR-27a-5p was confirmed as a tumor suppressor in NSCLC. Moreover, BBOX1-AS1-induced increase of cell proliferation, migration, invasion and EMT was greatly reversed due to the overexpression of miR-27a-5p. In addition, the suppressive effect of NSCLC progression owing to BBOX1-AS1 ...
miR‐27amiR‐142‐5pNAFLDNrf2oxidative stressdoi:10.1002/iub.2221Maryam TeimouriDepartment of Clinical Biochemistry, Faculty of Medicine Tehran University of Medical Sciences Tehran IranHossein HosseiniDepartment of Clinical Biochemistry, Faculty of Medicine Tehran University of Medical Sciences Tehran Iran...
miR-27a-5pendometrial cancerPolycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-age women. Women with PCOS have a 2.7-fold increased risk for developing endometrial cancer (EC). This study was performed to investigate the potential stimulatory effects of serum ...
Moreover, miR-27a-5p was overexpressed in the ceca of C. difficile–infected mice, correlating with intestinal interleukin 8 levels. Treatment of infected mice with the miR-27a-5p mimic reduced disease severity and intestinal inflammation. CONCLUSIONS. miR-27a-5p plays a crucial role in ...