miR-27a-5p 的高表达可能对重症疾病具有保护作用;miR-1246 的下调与有效的抗病毒细胞宿主防御相关;miR-21-5p 表达降低可能预防肺纤维化的发展;miR-423-5p 有望成为 SARS-CoV-2 感染早期的生物标志物。 然而,该研究也存在一定局限性,如未纳入重症患者、miRNA 在不同组织中的表达差异未充分研究、缺
说明:bta-miR-27a-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的翻译,从而起到转录后调控靶基因的表达。 miRNAs广泛存在于动物、植物、真菌...
miR-27a-5p was confirmed as a tumor suppressor in NSCLC. Moreover, BBOX1-AS1-induced increase of cell proliferation, migration, invasion and EMT was greatly reversed due to the overexpression of miR-27a-5p. In addition, the suppressive effect of NSCLC progression owing to BBOX1-AS1 ...
MiR-27a-5p has been known to influence cell apoptosis in various conditions, including liver ischemia-reperfusion injury [13], hypoxia-related heart diseases [14], and cancers [15,16]. Furthermore, research by Zhang et al. [17] delved into the regulatory mechanism of miR-27a-5p in ...
The miR-196a-5p- and miR-196b-55p-treated cells exhibited reductions of 35% (P = 0.047) and 44% (P = 0.0063), respectively. These data suggest that miR-196a-5p and miR-196b-5p play an important role in UGT2A1 regulation within the lung and potentially other aerodigestive tract ...
说明:cgr-miR-27a-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的翻译,从而起到转录后调控靶基因的表达。 miRNAs广泛存在于动物、植物、真菌...
miR-27a-5p was confirmed as a tumor suppressor in NSCLC. Moreover, BBOX1-AS1-induced increase of cell proliferation, migration, invasion and EMT was greatly reversed due to the overexpression of miR-27a-5p. In addition, the suppressive effect of NSCLC progression owing to BBOX1-AS1 ...