MiR-21 represents an intensively studied microRNA in many types of cancer, including non-small cell lung cancer (NSCLC). Its role as an oncogene is underlined in multiple studies reporting the upregulated expression of this sequence in patients diagnosed with this malignancy; moreover, several ...
miR-21 has been shown to regulate the progression of pancreatic caner by targeting tumor suppressor or oncogenes, playing a key role in cell proliferation, differentiation, migration, invasion and drug resistance of pancreatic cancer. Therefore, miR-21 will possibly be a potential biomarker for ...
mi R -·15 5 predic ts re currence an d unfavourabl e survival in' non··small cell lung cancer~J] .Eur J Can cer,2013,49(3) :604-615. [ 12] Li J,Huan g H,Sun L,et a1 .miR-21 indicates poor pro gnos is in
胃腺癌组织中miR一21的表达变化及意义刘汉山(武警江苏省总队医院,江苏扬州225003)山东医药2013年第53卷第47期摘要:目的观察胃腺癌组织中miR-21的表达变化,分析其临床意义。方法用荧光定量PCR和原位杂交法分别检测40例胃腺癌组织和癌旁正常组织中的miR-21表达,并分析miR-21表达水平与胃腺癌临床病理特征的关系。结果miR...
miR-21 has been implicated in the development and progression of various diseases, including cancer, cardiovascular disease, fibrosis, and inflammation. In cancer, miR-21 is frequently overexpressed and is associated with increased tumorigenesis, invasion, and metastasis. It has been shown to regulate...
【摘要】Objective To observe the expression level and diagnosis performance of serum exosomal miR-21 in lung cancer. Method Sera of 94 lung cancer patients,29 pulmonary tuberculosis patients,and 26 healthy controls from Nan Fang Hospital were collected. Exosomes in serum were purified and characterize...
andadhesionmoleculesinadvanced gastriccancer[J].EurJcancer.2006,42(2):256—263 YoshikawaR,NakanoY,TaoL,eta1.Hedgehogsignalactivationin oesophagealcancerpatientsundergoingneoadjuvantchemoradiotherapy [J].BrJCancer,2008,98:1670—1674 RosivatzE,BeckerI,Spechtk,eta1.Differentialexpressionofthe ...
MiR-21 is an oncomiR that is overexpressed in nearly all cancers including ATC. Accumulating evidence suggested that miR-21 has a role in cancer stemness state, apoptosis, cell cycle progression, and differentiation. Therefore, we evaluated the application of Off-miR-21 to sequester the microRNA...
ꎻ凋亡Physcioninhibitingbreastcancercellssurvivalandpromotingapoptosisviaregula~tingmiR~21expression BAIJieꎬYINGZi~weiꎬZHAOLinꎬLIWei~jieꎬWANGCongꎬXIEXian~xinꎬJIANGDa~qing ∗ (DepartmentofBreastSurgeryꎬCancerHospitalofChinaMedicalUniversityꎬLiaoningCancerHospital&In~stituteꎬShenyang110042ꎬ...
miR-21、miR-31在大肠癌和癌旁正常组 织中的表达和临床意义 分类号：R656.9 密级：一般 U D C ：617.55 编号：2010212451 广州医学院 硕士学位论文miR-21、miR-31在大肠癌及癌旁正常组 织中的表达及临床意义 研究生：宋韬 导师：胡伟民主任医师 申请学位级别：医学硕士年级：二零一零级 学科专业：外...