miR-15a-5p MicroRNAs (miRNAs) are small non-coding RNA molecules, approximately 22 nucleotides in length that regulate gene translation through silencing or degradation of target mRNAs. They are involved in multiple biological processes, including differentiation and proliferation, metabolism, hemostasis, ...
miR‐15a‐5p acts as a potential "master‐miR" regulating genes in the MK GPVI signaling pathway. Summary Background Megakaryocytes ( MK s) invest their progeny platelets with proteins and RNA s. Micro RNA s (miRs), which inhibit mRNA translation into protein, are abundantly expressed in MK...
目的探讨miR-15a-5p靶向乙酰肝素酶2(HPSE2)对宫颈癌细胞增殖,迁移和侵袭的影响.方法以人宫颈癌细胞系(Hela和SIHA)为研究对象,将miR-15a-5p mimic,miR-15a-5p inhibitor和HPSE2质粒转染进入细胞.分别采用CCK-8检测细胞活力,划痕实验和Transwell实验分别检测细胞迁移和侵袭能力,Western blot检测HPSE2表达,RT-qPCR检测...
1.miR-15a-5p和/或修饰的miR-15a-5p在制备治疗和/或预防眼底疾病的产品中的应用。 2.根据权利要求1所述的应用,其特征在于,所述的眼底疾病选自玻璃体病变、视网膜病变、视神经病变或脉络膜病变中的一种或两种以上。 3.根据权利要求1所述的应用,其特征在于,所述的眼底疾病选自早产儿视网膜疾病、视网膜新生血管疾...
tch-miR-15a-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:tch-miR-15a-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:tch-miR-15a-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
摘要 本发明公开了一种miR‑15a‑5p在提高CAR‑T细胞抗肿瘤能力中的应用,属于生物医学技术领域。本发明通过将Anti‑CD19CAR载体与miRNA‑15a‑5p抑制剂共转T细胞,发现miRNA‑15a‑5p抑制剂能够提高CAR‑T细胞内的CD28的表达,使T细胞在免疫过程中快速增值、活化,提高抗肿瘤能力。因此,miRNA‑15a‑5p...
miR-15a-5p promotes the proliferation,migration and invasion of cervical cancer cells by targeting HPSE2 引用 收藏 分享 摘要 目的探讨miR-15a-5p靶向乙酰肝素酶2(HPSE2)对宫颈癌细胞增殖、迁移和侵袭的影响。方法以人宫颈癌细胞系(Hela和SIHA)为研究对象,将miR-15a-5p mimic,miR-15a-5p inhibit...展开...
用trizol法提取三组细胞:anti-cd19car+mirna-15a-5pantagomir组、anti-cd19car+mirna-15a-5pantagomirnegativecontrol(antagomirnegative产品编号:mir03101-1-10,广州市锐博生物科技有限公司)组和野生型t细胞的总rna,逆转录成cdna,以β-actinmrna作为内参基因(β-actin上下游引物分别为:f:5’-gtggacatccgcaaagac...
miR‐15a‐5p is a potential "master‐miR" for specifically regulating GPVI ‐mediated MK ‐platelet signaling. Targeting miR‐15a‐5p may have therapeutic potential in hemostasis and thrombosis. 展开 关键词: GPVI integrin activation megakaryocytes microRNAs platelets ...
摘要 目的观察miR-15a-5p对胃癌细胞增殖的影响.方法将miR-15a-5pmimics,mimicscontrol,miR-15a-5pinhibitor,inhibitorcontrol分别转染至胃癌SGC-7901和BGC-82... 关键词miR-15a-5p / 胃癌 / 细胞增殖 收藏 文库来源 其他来源 免费下载 求助全文 miR-15a...