MicroRNA are small, non-coding, single-stranded RNAs that are estimated to regulate ~60% of the human genome. MiRNA profiling of monocyte-to-osteoclast differentiation identified miR-142-3p as a miRNA that is significantly, differentially expressed throu
Moreover, the downstream proinflammatory factors of miR-21 and miR-142a-3p were also regulated by lncRNA-SUMO3 and lncRNA-HDMO13. Our results provide a theoretical basis for exploring the molecular mechanism of grass carp lncRNAs regulating inflammation. 展开 ...
We then explored the potential role of miR-142a-3p in IL-EV-mediated induction of NET formation. Interestingly, miR-142a-3p induced significant NET formation (Figures 2B and 2C). In addition, miR-142a-3p promoted PMA-induced NET formation (Figure 2D). Furthermore, to assess the role ...
Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 exp... Aims: Exosome-mediated microRNA transfer is a recently discovered mode of cell-to-cell communication, in which microRNAs act as paracrine ...
The study showed the overexpression of eight platelet microRNAs in ACS (miR-142-3p; miR-107; miR-338-3p, miR-223-3p, miR-21-5p, miR-130b-3p, miR-301a-3p, miR-221-3p) associated with platelet reactivity and functionality. Our results show that the combined model based on miR-142-...
Functionally, miR-142-3p–mediated regulation of GARP is involved in the expansion of CD25<sup>+</sup> CD4 T cells in response to stimulation. The data indicate that miR-142-3p regulates GARP expression on CD25<sup>+</sup> CD4 T cells and, as a result, their expansion in response to...
The microRNA (miRNA) miR‐142‐3p has been shown to inhibit carcinogenesis by regulating various cellular processes, including cell cycle progression, cell migration, apoptosis, and invasion. It does so via targeting molecules involved in a range of signaling pathways. We surgically collected 20 ER...