16、与现有技术相比,本发明的益处在于:通过体内外实验明确了mir-137-3p激动剂能促进小胶质细胞吞噬过程,从而增强其对ad神经病理β-淀粉样斑块(aβ)的吞噬清除。 技术特征: 1.mir-137-3p激动剂在制备用于提高小胶质细胞吞噬能力的制剂中的应用。 2.如权利要求1所述的应用,其特征在于:所述mir-137-3p激动剂为双...
Dual-luciferase reporter assay was used to analyze the combination between miR-137-3p and specificity protein 1 (SP1), as well as SP1 and MCP-1. Results showed that number of recruited THP-1 cells after EA.hy926 cells treated by DBP was significantly higher than that in the control group...
miR-137-3pTau phosphorylationLipid nanoparticlesmiRNA deliveryIntroduction This study aimed to investigate the impact of miR-137-3p on the pathogenesis of Alzheimer's disease (AD) and develop a pioneering in vivo delivery method for its therapeutic potential. Methods This study was initiated by ...
tgu-miR-137-3p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:tgu-miR-137-3p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:tgu-miR-137-3p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对...
货号:lva-miR-137-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:lva-miR-137-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
目的:通过研究完全弗氏佐剂(Complete Freund's Adjuvant,CFA)模型大鼠中下丘脑弓状核(hypothalamicarcuatenucleus,ARC)内的miR-137-3p、miR-195-5p与Src酪氨酸蛋白激酶和NMDA受体(N-methyl-D-aspartic acid receptor,NMDAR)的亚基GluN1、GluN2A、GluN2B的表达及其相互关系,从而探讨miR-137-3p,miR-195-5p如何通过调...
目的探讨黄连素(BBR)对糖尿病脑病(DE)患者miR-132-3p,miR-137表达及胰岛素抵抗的影响.方法选取糖尿病脑病患者110例作为研究对象,随机分为对照组与观察组,各55例.对照组口服二甲双胍及基础血糖控制治疗,观察组在对照组的基础上联合口服黄连素片治疗.30 d治疗后,进行组间临床疗效,血糖指标,胰岛素功能,胰岛素抵抗指数...
The present study found that MIR137HG was overexpressed in gastric cancer (GC) samples than surgical margin (SM) samples. It could promote the abilities of migration, invasion, and colony formation in gastric cancer cell lines. At the same time, the expression of miR-2682-3p was negatively ...
The present study found that MIR137HG was overexpressed in gastric cancer (GC) samples than surgical margin (SM) samples. It could promote the abilities of migration, invasion, and colony formation in gastric cancer cell lines. At the same time, the expression of miR-2682-3p was negatively ...