miR-10b expression in breast cancer stem cells supports self-renewal through negative PTEN regulation and sustained AKT Activation. 2016, 17(5): 648-658I. Bahena-Ocampo, M. Espinosa, G. Ceballos-Cancino, F. Lizarraga, D. Campos- Arroyo, A. Schwarz, V. Maldonado, J. Melendez-Zajgla, P...
1. miR-10b expression in breast cancer stem cells supports self-renewal through negative PTEN regulation and sustained AKT activation (vol 17, pg 648, 2016) [J] . Bahena-Ocampo Ivan, Espinosa Magali, Ceballos-Cancino Gisela, EMBO reports . 2016,第7期 机译:乳腺癌干细胞中miR-10b的表达通...
significant. 【Results】 1.The expression of miR-1 0b was 3.87-fold higher in breast cancer no significant difference俨>0.05). 2.The expression of HOXDlomRNA was 0.35一fold in breast cancer tissues than that in para—carcinoma breast tissues,the difference was significant俨<0.05),and in ...
breast cancer [22] and overexpression of miR-10a promoted cell migration and invasion of hepatoma cancer cell lines [23] and cervical cancer cell linesin vitro[24]. On the other hand, miR-10b was upregulated in pancreatic cancer and B-cell chronic lymphocytic leukemia [20] In addition, miR...
There is a pressing need for further studies to categorize and validate circulating microRNAs (miRs) in breast cancer patients that can be one of the novel strategies for cancer screening and monitoring. The present study is aimed to investigate the expression of the circulating candidate microRNAs ...
(miR一195)intissuesofpatientswithbreastinvasiveductalcarcinoma. Methods Samplesofcancerandparaneoplastictissuesof 40breastcancerpatientswerecollected,andtheexpressionofmiR一10bandmiR195inthetissueswasdetectedbyusingreverse transcriptasePCR,therelationshipbetweentheexpressionandclinic。pathologywasanalyzed. ...
It is important to identify genes regulating metastasis and invasion in order to curtail metastatic spread of cancer cells. Methods This study investigated the association between RUNX2 and miR-10a/miR-10b and the risk of breast cancer relapse. Expression levels of RUNX2 and miR-10a/b in108 ...
Expression levels of RUNX2 and miR-10a/b individually or jointly are potential prognostic factors for predicting breast cancer recurrence. Data from in vitro studies support the notion that RUNX2 promoted cell motility by upregulating miR-10a/b....
The value of serum CA153and miR-10b in the diagnosis of early breast cancer CHENG Wen1B4N Guangrui2ZENGAn'gu/WANG Yi1LI Pan1 1.Thyroid and BreasL Surgery DeparLmenL,AffiliaLed HospiLal of Panzhihua UniversiLy Panzhihua InLegraLed HospiLal of TradiLional Chinese and WesLern Medicine,Sichuan...
The data demonstrated that miR-10b and miR-145 regulate the functional properties of shERβ ΜDA-MB-231 breast cancer cells, highlighting the novel role of ERβ, along with epigenetic alterations of miRNAs in breast cancer cell behavior.