The reversion experiment shows that miR-532-3p/SERPINE1 regulates the ECM RECEPTOR INTERACTION pathway and affects the malignant progression of colon adenocarcinoma cells. Conclusion As the upstream regulatory gene of SERPINE1, miR-532-3p inhibits the proliferation, migration and invasion of colon ...
No.10 miR396↓ Interaction GIF miR396-GRF 调控途径通过影响细胞扩增以及 GA 和 IAA 激素合成,从而影响植物营养生长,雄性生殖以及果实发育等生长发育过程.并且 GIF 蛋白 与 GRF 蛋白会形成功能复合物从而增强 GRF 功能 The miR396-GRF regulatory pathway affects vegetative growth,male reproduction and fruit ...
LiGL,LiuJ,XieJ,etal.InhibitoryeffectofmiR-122-5ptargeting ADAM10toregulateNotchsignalingpathwayonepithelial-mesen- chymaltransitionofhumanovariancancercellSKOV-3[J].Acta UniversityMedicalAnhui,2021,56(1):54-59.DOI:10.19405/j. cnki.issn1000-1492.2021.01.011. [9] 陈劭赓,何荣琦,张万飞,等.miR-122-...
[13]Zhou LY, Zhang FW, Tong J, et al. MiR-191-5p inhibits lung adenocarcinoma by repressing SATB1 to inhibit Wnt pathway[J]. Mol Genet Genomic Med, 2020, 8(1): e1043. [14]Tong L, Han WZ, Wang JL, et al. MicroRNA-365 in...
miR172 signals are incorporated into the miR156 signaling pathway at the SPL3/4/5 genes in Arabidopsis developmental transitions[J]. Plant Molecular Biology, 2011, 76(1/2):35-45. [78]Kasschau KD, Xie Z, Allen E, et al. P1/HC-Pro, a viral suppressor of RNA silencing, interferes ...
[27] Molkentin JD, Lu JR, Antos CL,et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy[J] Cell, 1998, 93(2): 215-28. [28] keda S, He A, Kong SW,et al. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes[J]...
Vertebrate multiciliated cells (MCCs) contribute to fluid propulsion in several biological processes. We previously showed that microRNAs of the miR-34/449 family trigger MCC differentiation by repressing cell cycle genes and the Notch pathway. Here, usi
Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa‐miR‐6887‐3p Haixia Li, Jinghui Liang, Jiang Wang, Jingyi Han, Shuang Li, Kai Huang, Chuanyong Liu Canc...
目的 探讨miR-338-5p在结直肠癌组织中的表达状况,以及miR-338-5p过表达对结肠癌细胞系HCT116和SW620增殖、凋亡及细胞周期的影响。 方法 使用实时定量PCR方法检测miR-338-5p在40例临床诊断为结直肠癌患者配对癌组织及癌旁组织中的表达情况。随后使用miR-338-5p-mimics转染结肠癌细胞系HCT116和SW620,确认过表达成...