miR-542-5p 促进 Th17 细胞极化:体外实验表明,miR-542-5p 能够促进 Th17 细胞的分化。生物信息分析发现了一些 Th17 细胞分化的调节因子,其中 FOXO1 和 TEAD1 是 miR-542-5p 的靶基因。抑制 miR-542-5p 表达时,FOXO1 和 TEAD1 的表达上升;上调 miR-542-5p 表达时,这两个基因的表达下降,说明
说明:cgr-miR-542-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的翻译,从而起到转录后调控靶基因的表达。 miRNAs广泛存在于动物、植物、真...
mmu-miR-542-5p inhibitor 是一种全链经过甲氧基修饰的成熟miRNA的互补单链。miRNA inhibitor通过特异性结合成熟miRNA,阻止miRNA与其靶基因的互补配对,从而抑制miRNA的功能,可用于miRNA 功能缺失性(loss-of-function)研究。 产品介绍 mmu-miR-542-5p inhibitor 是一种全链经过甲氧基修饰的成熟miRNA的互补单链。miRNA...
MiR-542-5p is one of the X-linked miRNAs, which plays a crucial role in immune regulation [19]. It has been shown that miR-542-5p can regulate the differentiation process of monocytes [20]. In fact, DNA damage, T-cell abnormalities, and mitochondrial homeostasis are important pathological ...
英文别名: mmu-miR-542-5p miRNA Inhibitor 中文名: 中文别名: CBNumber: CB217309176 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 mmu-miR-542-5p miRNA Inhibitor化学性质 安全信息mmu-miR-542-5p miRNA Inhibitor性质、用途与生产工艺 mmu-miR-542-5p miRNA Inhibitor 上下...
Here, we utilize unbiased approaches to identify the specific pristimerin responsible for anti-cancer effect, and identify miR-542-5p as a silence signal of DUB3. The miR-542-5p/DUB3 signaling axis forms a "sensor and effec- tor" circuitry by pristimerin treatment to suppress breast cancer...
3.4功能性外泌体中miR-1249-5p基因表达 如图3所示,与对照组比较,模型组外泌体miR-1249-5pmRNA表达水平显著下降(P<0.01);与模型组比较,各给药组外泌体miR-1249-5pmRNA表达水平明显增加(P<0.05、0.001),而含药血清低剂量组miR-1249-5pm...
Here, we utilize unbiased approaches to identify the specific pristimerin responsible for anti-cancer effect, and identify miR-542-5p as a silence signal of DUB3. The miR-542-5p/DUB3 signaling axis forms a "sensor and effec- tor" circuitry by pristimerin treatment to suppress breast cancer...