He Y, Chen X, Yu Y, Li J, Hu Q, Xue C, Chen J, Shen S, Luo Y, Ren F, et al. LDHA is a direct target of miR-30d-5p and contributes to aggressive progression of gallbladder carcinoma. Mol Carcinog. 2018;57(6):772-83....
He Y, Chen X, Yu Y, Li J, Hu Q, Xue C, Chen J, Shen S, Luo Y, Ren F, et al. LDHA is a direct target of miR-30d-5p and contributes to aggressive progression of gallbladder carcinoma. Mol Carcinog. 2018;57(6):772-83....
LDHA: lactate dehydrogenase A EV: extracellular vesicles References Sia D, Villanueva A, Friedman SL, Llovet JM. Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis. Gastroenterology. 2017;152(4):745–61. Article CAS PubMed Google Scholar Llovet JM, Zucman-Rossi...
KLF4 is implicated in tumor progression of pancreatic cancer, but the molecular regulatory mechanism of KLF4 needs to be further specified. We aimed to probe molecular regulatory mechanism of KLF4 in malignant progression of pancreatic cancer. qRT-PCR or
c Real-time qPCR analysis of the effect of miR-210-3p/GPD1L axis on GLUT1 and LDHA mRNA expression in MDA-MB-231 and Hs578T cells. d Western blotting analysis of the effect of miR-210-3p/CYGB axis on p53 expression in MDA-MB-231 and Hs578T cells. e Real-time qPCR analysis of...
miR-30c-5pglucose metabolismWarburg effectLDHAINVASIONGastric cancer (GC) is a human malignancy which is associated with high mortality rate and poor prognosis. In addition to surgery, chemo- and radio-therapies are effective strategies against GC at advanced or metastatic stage. Taxol is a ...
LncRNA TMPO-AS1 Promotes Triple-Negative Breast Cancer by Sponging miR-383-5p to Trigger the LDHA Axisdoi:10.31557/APJCP.2024.25.8.2929Vats, PrernaSingh, JaiSrivastava, Sandeep K.Kumar, AshokNema, RajeevAsian Pacific Journal of Cancer Prevention...
miR-30a-5p overexpression sensitized CRC cells to 5-Fu treatment and targeted the glycolysis key enzyme, LDHA. Rescue experiments showed that restoring LDHA in CRC cells which were overexpressing miR-30c-5p successfully overridden 5-Fu resistance. Importantly, restoring miR-30a-5p in NOP14-AS1-...
In addition, chidamide suppressed the expression of LDHA and significantly decreased the glycolysis of TNBC cells. Collectively, the results of the present study demonstrated that chidamide reprogramed glucose metabolism, partially by targeting the miR-33a-5p/LDHA pathway, in TNBC. These findings ...
Conclusions:LINC01128 promotes the proliferation, migration, invasion, and EMT of PC by regulating the miR-561-5p/LDHA axis, suggesting LINC01128 may be a new prognostic marker and therapeutic target in PC.doi:10.1186/s12935-022-02490-5Min.Zhong...