Ischemic cerebral small-vessel disease accounts for a third of acute cerebral ischemic events and contributes to the development of cognitive decline and dementia. Cerebral small-vessel disease can be visualized on MRI studies as lacunar infarcts, white matter lesions and cerebral microbleeds. In ...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
Structural retinal changes in cerebral small vessel disease Article Open access 03 June 2022 Introduction Presently, the pathogenesis of cerebral small vessel disease (SVD) in humans is not completely understood, in part due to the difficulty in imaging in vivo the cerebral microvasculature. SVD is...
1 However, the biological processes driving an acute biomechanical injury to a chronic, lifelong pathology associated with late neurodegenerative disease remain uncertain.2,3 Among TBI-related pathologies, vascular injury is recognized as a common pathology, with outcomes ranging from macrova...
have been described3. Impaired cerebral glucose metabolism37, mitochondrial dysfunction, and increased oxidative stress have all been observed8. In addition to neurodegenerative brain changes, dementia is frequently associated with vascular pathologies such as small vessel disease (multiple or single infarcts...
(COPD), chronic kidney disease, cancer, substance abuse, alcoholism, inability to speak or communicate, blindness or impaired vision even with corrective lenses, hearing loss, inability to sit stably due to physical conditions such as chronic pain or low back pain, and those who had undergone ...
Association between Nine Types of TCM constitution and five chronic diseases: a correspondence analy sis based on a sample of 2,660 participants. Evid Based Complement Alternat Med. 2017;2017(4):1–7. 32. Wang Q, Yao S. Molecular basis for cold-intolerant yang-deficient constitution of ...
Objective To discuss the correlation of mild cognitive impairment and plasma homocysteine( Hcy) and highsensitivity C-reactive protein( hs-CRP) level in patients with cerebral small vessel disease. Methods From March 2015 to July 2015,100 cases of cerebral small vessel disease patients were collected...
The pathophysiology of amnestic Mild Cognitive Impairment (aMCI) is largely unknown, although some papers found signs of immune activation. To assess the cytokine network in aMCI after excluding patients with major depression (MDD) and to examine the imm
Twenty-Four Hours of Mild Hypothermia in Unsedated Newborn Pigs Starting after a Severe Global Hypoxic-Ischemic Insult Is Not Neuroprotective MARIANNE THORESEN, SAULIUS SATAS, ELSE MARIT LØBERG, ANDREW WHITELAW, DOMINIQUE ACOLET, CARL LINDGREN, JULIET PENRICE, NICOLA ROBERTSON, EGIL HAUG, AND ...