Increased cellular levels of MicroRNA-9 and MicroRNA-221 correlate with Cancer stemness and predict poor outcome in human breast Cancer Cell. Physiol. Biochem., 48 (5) (2018), pp. 2205-2218 CrossrefView in Scopu
Down-regulation of these enzymes by microRNA-9/9* affects the U34 modification status of non-mutant tRNAs and contributes to the MELAS phenotype. Anti-microRNA-9 treatments of MELAS cybrids reverse the phenotype, whereas miR-9 transfection of wild-type cells mimics the effects of siRNA-...
The level of microRNA-9-5p (miRNA-9-5p) in brain tissues is significantly changed in the chronic phase after traumatic brain injury (TBI). However, the effect of miRNA-9-5p on brain function after TBI has not been elucidated. In this study, we used a con
多变量分析显示,9 - c - miR 预测概率每增加 5%,I 期肺癌风险在 MUG 和 HUM 队列中分别提升 29%(p < 0.0001)和 25%(p = 0.0224)。 讨论与研究意义 该研究构建的 9 - c - miR 标志物通过严格的多平台、多中心验证,在不同临床特征和检测平台中展现出稳定的诊断效能,且与 LD - CT 筛查结合可显著...
The functional significance of microRNA-9 (miR-9) during evolution is evidenced by its conservation at the nucleotide level from flies to humans but not its diverse expression patterns. Recent studies in several model systems reveal that miR-9 can regulate neurogenesis through its actions in neural...
The objective of the study was to investigate the role of microRNA-9 (miR-9) targeting forkhead box O1 (FOXO1) in the proliferation, migration, and invasion of breast cancer cells. Methods Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to determine the expressions of ...
MicroRNA-9 (miR-9), enriched in central nerve system (CNS) [28], contributes likely to multi-pathological processes including the neurogenesis [29], proliferation [30], migration and differentiation of neural progenitor cells [31], drug adaption [32], adult brain plasticity [33], neural cell...
MCPIP1 alleviated lipopolysaccharide-induced liver injury by regulating SIRT1 via modulation of microRNA-9. (2019).[10.1002_jcp.搜索 J Cell Physiol. 2019;1–13. wileyonlinelibrary.com/journal/jcp © 2019 Wiley Periodicals, Inc. | 1Received: 17 February 2019|Revised: 22 April 2019|Accepted:...
MicroRNA-9调节Navl.1和Navl.2膜转运的分子机制研究 图1钠通道基本结构图【24】 Figure 1The basic structure of sodium channel Navl.1在胞体和树突上以及郎飞氏结节点部位表达,Navl.2在成年人的 中枢神经系统中大量表达,特别是在皮层和海马区,主要定位在无髓鞘的轴突 以及聚集在突触起始端,维持动作电位时程的...
MicroRNA-9 (miR-9), enriched in central nerve system (CNS) [28], contributes likely to multi-pathological processes including the neurogenesis [29], proliferation [30], migration and differentiation of neural progenitor cells [31], drug adaption [32], adult brain plasticity [33], neural cell...