Increased cellular levels of MicroRNA-9 and MicroRNA-221 correlate with Cancer stemness and predict poor outcome in human breast Cancer Cell. Physiol. Biochem., 48 (5) (2018), pp. 2205-2218 CrossrefView in ScopusGoogle Scholar [18] J.M. Gwak, H.J. Kim, E.J. Kim, Y.R. Chung, ...
结论电针曲池、足三里穴可促进室管膜下区神经干细胞增殖,其作用可能通过下调miR-9表达。%Objective To investigate the effect of electroacupuncture (EA) at Quchi (LI11) and Zusanli (ST36) acupoints on rats with fo-cal cerebral ischemia, and whether it was mediated by microRNA-9 (miR-9) ...
3 reagents referenced in The ROS-sensitive microRNA-9/9* controls the expression of mitochondrial tRNA-modifying enzymes and is involved in the molecular mechanism of MELAS syndrome.
我们发现miR-9(micro RNA-9,miR-9)被预测为靶向Fstl1的潜在miRNA之一.miR-9在心梗组织中表达下降,且与Fstl1表达呈负相关性.荧光素酶活性检测进一步证实miR-9靶向调控Fstl1.H9c2细胞中miR-9呈高表达的同时Fstl1表达下降,反之亦然.这表明miR-9靶向调控Fstl1且呈负相关性.为了进一步分析miR-9在缺氧细胞中的作用...
The functional significance of microRNA-9 (miR-9) during evolution is evidenced by its conservation at the nucleotide level from flies to humans but not its diverse expression patterns. Recent studies in several model systems reveal that miR-9 can regulate neurogenesis through its actions in neural...
MicroRNA-9调节Navl.1和Navl.2膜转运的分子机制研究 图1钠通道基本结构图【24】 Figure 1The basic structure of sodium channel Navl.1在胞体和树突上以及郎飞氏结节点部位表达,Navl.2在成年人的 中枢神经系统中大量表达,特别是在皮层和海马区,主要定位在无髓鞘的轴突 以及聚集在突触起始端,维持动作电位时程的...
Sun et al. Molecular Neurodegeneration (2015) 10:36 DOI 10.1186/s13024-015-0032-9 RESEARCH ARTICLE Open Access MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion Li-Hua Sun1*, Mei-Ling Yan1, Xue-...
MicroRNA-9 (miR-9), enriched in central nerve system (CNS) [28], contributes likely to multi-pathological processes including the neurogenesis [29], proliferation [30], migration and differentiation of neural progenitor cells [31], drug adaption [32], adult brain plasticity [33], neural cell...
Purpose The objective of the study was to investigate the role of microRNA-9 (miR-9) targeting forkhead box O1 (FOXO1) in the proliferation, migration, and invasion of breast cancer cells. Methods Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to determine the expressio...
MicroRNA-9调控室管膜下区干细胞增殖在电针治疗局灶性脑缺血中的作用 目的:探讨电针曲池,足三里穴是否是通过介导microRNA-9(miR-9)调控缺血再灌注损伤大鼠室管膜下区神经干细胞增殖来发挥神经保护作用.方法52只Sprague-Dawley大鼠随机分... 黄佳,郑薏,姚建宁,... - 《中国康复理论与实践》 被引量: 3发表: ...