This study explores how microRNA-15b-5p (miR-15b-5p) functions in modulating the proliferation, migration, inflammatory response, and ECM deposition of ASM cells. MiR-15b-5p and yes-associated protein 1 (YAP1) mRNA expression levels in tumor necrosis factor alpha (TNF-伪)-induced ASM cells ...
In the current study, we determined the role of mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs) containing microRNA (miR)-15b-5p in DN. After extraction and identification of MSC-derived EVs, mouse podocyte line MPC5 was selected to establish an in vitro high-glucose (HG)...
doi:10.1155/2024/9892106BioMed Research InternationalBioMed Research International
Abstract 332: A Data Mining Strategy Identifies microRNA-15b-5p as a Potencial Bio-Marker in Non-Ischemic Heart FailureBiomarkersHeart failureMicroRNAAdvances in bioinformatics has provided us with large databases that characterize the complex genetic and epigenetic changes associated with human diseases....
Transfection with miR-15b-5p suppressed migration and tube formation, which were attenuated by the miR-15b-5p inhibitor. miR-15b-5p down-regulated VEGF signaling via the AKT pathway; thus, the miR-15b-5p RNA inhibitor could be a possible therapeutic agent for cardiovascular disease....
MicroRNA-15b-5pBRMS1DAPK1MetastasisExtracellular vesicles (EVs) derived from tumor-associated macrophages are implicated in the progression and metastasis of gastric cancer (GC) via the transfer of molecular cargo RNAs. We aimed to decipher the impact of microRNA (miR)-15b-5p transferred by M2 ...
Transfection with miR-15b-5p suppressed migration and tube formation, which were attenuated by the miR-15b-5p inhibitor. miR-15b-5p down-regulated VEGF signaling via the AKT pathway; thus, the miR-15b-5p RNA inhibitor could be a possible therapeutic agent for cardiovascular disease....
成骨分化目的:探讨microRNA (miR)-15b-5p对大鼠来源骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)成骨分化的调控功能,并构建壳聚糖/miR-15b-5p纳米粒子,研究该纳米粒子对于大鼠BMSCs成骨分化的影响.方法:提取大鼠原代BMSCs并诱导其成骨分化,检测miR-15b-5p在成骨分化过程中的表达变化.再在大鼠...
Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlapdoi:10.1111/all.14520Keita HiraiToshihiro ShiraiTakayuki ShimoshikiryoKunihiko Itoh
Tumor-derived exosomal microRNA-15b-5p augments laryngeal cancer by targeting TXNIP. Cell Cycle. 2020;21(7):730-740. doi: 10.1080/15384101.2021.2022845 Since publication, significant concerns have been raised about the integrity of the data and reported results in the article. When approached for...