MicroRNA-133a inhibits cell proliferation,colony formation ability,migration and invasion by targeting matrix metallopeptidase 9 in hepatocellular carcinoma[J].Mol Med Rep 2015,11(5).Chen X, Bo L, Zhao X, Chen Q. MicroRNA-133a inhibits cell prolif- eration, colony formation ab...
microRNA-133a与骨质疏松症 基金项目：国家自然科学基金（８１７０２１３４）；安徽医科大学校基金临床科学基金（２０２０ｘｋｊ１８３）作者单位：２３００００合肥，安徽医科大学第一附属医院创伤骨科 通信作者：张月雷，Ｅ⁃ｍａｉｌ：ｏｒｔｈｏｚｈａｎｇ５２３３＠１６３．ｃｏｍＤＯＩ：１０ ３９６９／ｊ．ｉｓｓｎ．...
(4):748~51自发性高血压大鼠心肌组织microRNA-133a与TGF-蛋白表达的改变及意义谭文鹏,杨侃,(广州医学院第三附属医院心内科,广东广州510150;陈唏明,陈次滨中南大学湘雅三医院心内科,湖南长沙410013)[摘要]目的:观察mieroRNA-133a(miR-133a)与转化生长因子一Bl(transforminggrowthfactorpl,TGF-p1)蛋白在自发性高血压...
MicroRNA-133a (MiR-133a) is proven to exhibit a decreasing tendency in several cancers, as well as pancreatic cancer. Through the present study, we inspected performance for serum miR-133a in diagnosing pancreatic cancer. Serum samples were collected from 110 pancreatic cancer and 64 healthy ...
Overexpression of microRNA- 133a inhibits ischemia-reperfusion-induced cardiomyocyte apoptosis by targeting DAPK2. J Hum Genet 2015; 60: 709-716.S. Li, F.Y. Xiao, P.R. Shan, L. Su, D.L. Chen, J.Y. Ding, Z.Q. Wang, Overexpression of microRNA-133a inhibits ischemia-reperfusion-...
As a pathologic phenotype is generally regulated by multiple signaling pathways, in this study we identified a microRNA regulating multiple target genes within cardiac hypertrophic signaling pathways. microRNA-133a is known to play a crucial role in cardiac hypertrophy. However, the role of microRNA...
背景血管内皮细胞凋亡促进动脉粥样硬化(Atherosclerosis,AS)的形成,引起一系列心血管疾病,成为人类健康的巨大威胁.微小RNA-133a(microRNA-133a,miR-133a)是一类非编码RNA,其参与AS病理过程,然而具体的分子机制不详.中药红景天苷(Salidroside,SAL)具有显著抗AS作用,药理机制至今尚不明了.目的1.探讨miR-133a参与内皮细...
目的了解远洋船员高血压的流行现状及其主要影响因素,初步探讨高血压与血清microRNA21、microRNA133a的关系。 方法于2014年1至6月,选取在福建某国际旅行卫生保健中心进行体检的780名远洋船员进行健康检查及问卷调查;采用Taqman实时荧光定量聚合酶链式反应(RT-qPCR)技术测定高血压船员血清microRNA21、microRNA33a表达水平。
FULL PAPER British Journal of Cancer (2014) 110, 189–198 | doi: 10.1038/bjc.2013.676 Keywords: esophageal squamous cell carcinoma; FSCN1; MMP14; invadopodia; anti-oncomir; prognosis MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer ...
Using in vitro, in vivo and patient-based approaches, we investigated the potential of circulating microRNAs (miRNAs) as surrogate biomarkers of myocardial steatosis, a hallmark of diabetic cardiomyopathy. We analysed the cardiomyocyte-enriched miRNA sig