Microfluidic-based in vitro diagnostic technologyDiagnostic performanceTo investigate the clinical application value of microfluidic-based in vitro diagnostic (IVD) technology in pathogenic detection of respiratory tract infections.#A total of 300 clinical samples, including blood, bronchoalveolar lavage fluid,...
In this context, microfluidic-based in vitro models of the blood–brain barrier (BBB) are of particular interest as they provide an innovative approach for conducting research related to the brain, including modeling of neurodegenerative diseases and high-throughput drug screening. Here, we present ...
To simulate physiological human eye conditions such as temperature, tear volume and flow rate, drug release tests were carried out in a novel microfluidic cell.ResultsResults showed that a) HEMA based hydrogel allows a drug release up to 10 hours with predicted concentrations in the eye as >129...
Fritz, V.et al.A microfluidics-based in vitro model of the gastrointestinal human–microbe interface.
A microfluidic-based neurotoxin concentration gradient for the generation of an in vitro model of Parkinson's disease. Biomicrofluidics 5, 22214 (2011). Article PubMed CAS Google Scholar Chen, S. & Lee, L.P. Non-invasive microfluidic gap junction assay. Integr. Biol. (Camb) 2, 130–138 ...
A completely in vitro ultrahigh-throughput droplet-based microfluidic screening system for protein engineering and directed evolution D. A completely in vitro ultrahigh-throughput droplet-based microfluidic screening system for protein engineering and directed evolution . Lab Chip. 12 , ... A Fallah-Arag...
Pepin, Y. Chen: A microfluidic mammalian cell sorter based on fluorescence detection, Microelectron. Eng. 73, 852–857 (2004) Google Scholar D. Lipomi, R. Martinez, L. Cademartiri, G. Whitesides: Soft lithographic approaches to nanofabrication. In: Polym. Sci. Compr. Ref., Vol. 10 (...
In addition, it was shown that culturing epithelial cells in different 2D patterns and initialing EMT influences the spatial pattern of EMT [21]. Based on the influences of tissue geometry observed in these examples, it is important to develop in vitro models with improved physiologically relevant...
All of the results show that TTS plays an important role in the treatment of cervical cancer. Based on this study of its efficacy and mechanism of action, combined with modern clinical treatment, these results provide a basis for the use of TTS in the treatment of cervical cancer [Fig. 1...
In view of this, we present here a comprehensive review on fluid mixing methods based on passive and active devices. We start with a look at the working principle of active methods (magnetism, acoustics, electricity, and heat) and passive methods. Then, we provide examples to explain how ...