select article Monitoring of multiple bacteriocins through a developed dual extraction protocol and comparison of HPLC-DAD with turbidometry as their quantification system Research articleAbstract only Monitoring of multiple bacteriocins through a developed dual extraction protocol and comparison of HPLC-DAD ...
• Changes to time/temperature incubation periods, or enrichment media. • In cases where the sample preparation and/or the extraction procedure/analytical method is modified from the existing test procedure and protocol, i.e the new method should demonstrate that the modifications do not adve...
In our protocol, the turnaround time was 45–51 h, which included 39 h of Illumina MiSeq sequencing. Current sequencing technologies and mNGS pipelines allow an even faster time to result of < 30 h [42] with Illumina or ~ 6 h with Oxford Nanopore [43], allowing identification of ...
The protocol has demonstrated to be a comprehensive and valuable tool in validating, from a microbial point of view, a sterile-compounding technology. This study might represent an important benchmark in developing a contamination control strategy, as required, for example, in the Performance ...
As a standard protocol followed in our institute, the diagnosis of endophthalmitis was based on the presence of pain, inflammation including anterior chamber cellular reaction and flare and vitreous cells or exudates, decrease in visual acuity and loss of media clarity with or without the presence ...
Scheme 1. General amide coupling protocol for the synthesis of compound series 2 and 3. Reagents and conditions: EDCI, DMAP, DMF, 25 °C, 18 h, average yield of 49%. Download: Download high-res image (191KB) Download: Download full-size image Scheme 2. General procedure for boc-...
which is essential for replacing a compendial method with a new method. This is either in relation to the qualification of the method itself or in relation to testing samples against a specific method.17With this it is important to plan and to devise a suitable vali...
Besides, initiatives such as the Environmental Food Protocol and the Product Environmental Footprint (PEF) pilots (European Commission 2016) encourage the environmental life cycle-based assessment of food products [130, 131]. UNEP/ SETAC Life Cycle Initiative [132] has also published several papers ...
With these baseline results, in particular by sampling contact materials and hands when food handlers are using good manufacturing practices (e.g., changing gloves between handling raw and cooked products, hand washing according the protocol, and changing cutting boards during service when there is ...
aseptic preparationcompounding robotssterile productiondispensing robotsgood distribution practice (gdp)Objectives To design and execute a comprehensive microbiological validation protocol to assess a brand-new sterile compounding robot in a hospital pharmacy environment, according to ISO and EU GMP standards. ...