Mice are bothersome and costly because they contaminate a great deal of food for humans—from our crops to our cupboards. They chew holes in wires and destroy houses. They also carry diseases and bacteria. Read Next 3 Steps to Banish Rats and Mice from Your Shed, Barn, and Farm ...
Deafness is one of the most heterogeneous diseases known in humans, and study of the many deaf mouse mutants will help unravel the molecular basis of the pathology, an essential first step towards a rational approach to treatment.doi:10.1007/0-387-21853-X_8Karen P. Steel...
The work has significant implications for the development of future drugs and treatments. In the long term, it may pave the way for anti-aging strategies aimed to activating cells to protect telomeres, and potentially extend lifespans. Zhu noted that many diseases originate at the cellular level,...
This indicated that germ cell nests persist in aged ovary but are unable to assemble as follicles. This eventually leads to senescence in mice and menopause in humans. These results could explain recent findings of Castillo-Fernandez et al. [13] who reported a distinct population of oocytes ...
Mice across the city carry numerous dangerous diseases including shigella, salmonella, clostridium difficile and leptospira, which cause fever and gastrointestinal distress in humans, according to the study published by mBio, a journal of the American Society for Microbiology. ...
Loud sounds suggest danger, which these pests want to avoid. Mice prefer to be alone, away from humans and animals, so being around a lot of noise is not ideal. High-pitched noises may affect rodents, but research has shown the effects are often overcome within a day or so because the...
The development of humanized mice with functional human immune systems (generated by the engraftment of human lymphoid tissues, HSCs or peripheral blood mononuclear cells) provides an opportunity to carry out translational research on human immunity and autoimmune diseases, and for the study of the bio...
Passage 4主题:眼疾基因新发现Studying the DNA of 300 mice has flagged up genes(基因) which have been linked to hereditary(遗传的) sightloss for the firs time. Researchers say because mice's genes are so similar to humans', their findings could lead to thetreatment of more genetic diseases....
Alzheimerʼns disease: humans to transgenic mice In humans, Alzheimerʼns disease (AD) progresses over decades, resulting in synaptic dysfunction eventually leading to neuronal loss. Despite the large number of longitudinal aging studies in humans, the lack of cognitive measures coordinated with symptom...
Singh said the mouse model should provide an opportunity for the development of preventive and therapeutic drug development strategies to augment mitochondrial functions for the treatment of aging-associated and other diseases. In humans, a decline in mitochondrial functions is seen during aging, and mi...