四种消毒剂对小鼠肝炎病毒MHV-A59的杀灭效果,四种消毒剂对小鼠肝炎病毒MHV-A59的杀灭效果4种,效果,杀灭,MHV,mhv,消毒剂的,消毒剂,消毒剂对,肝炎病毒,肝炎..
Coronaviruses produce both acute and chronic diseases in various animal species. A recent review summarizes the biology and pathogenesis of coronaviruses.1Of special interest is the chronic demyelinating disease produced by mouse hepatitis virus (MHV) in rodents. This model has been used to study th...
摘要:目的应用藏茵陈对MHV—A59病毒感染湿热证小鼠模型进行治疗,通过实验初步探讨该药对小鼠病毒性肝炎的 干预机制。方法将32只小鼠随机分为正常组、模型组、阳性组和藏茵陈组。分别在造模前后测定小鼠的肛温和体重, 并在造模后分别用试剂盒测定小鼠血清肝功能两项、小鼠肝匀浆MDA含量和SOD活性,通过HE染色后光镜观察...
MHV-A59 causes a chronic demyelinating disease in mice which is accompanied by persistence of viral genome in white matter. As part of the investigation into the mechanism of viral persistence, infection of glial cells, probable targets for chronic infection, was studied by the use of mixed glia...
Recombinant coronaviruses inf-MHV-A59 (A59) and inf-ns2-H126R (ns2-H126R) have been described previously (Roth-Cross et al., 2009; Schwarz et al., 1990). ( Show abstract The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is ...
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MHV-A59 1. The standard strainMHV-A59was used to infect 6 strains of mice(BALB/c,C57,nu/nu,NIH-Ⅲ,IL-4T and IL-10T) in three paths(belly,oral route and nasal instillation). 采用MHV-A59标准毒株通过3种途径(腹腔、滴鼻、灌胃)对6个品系的实验小鼠(BALB/c、C57、nu/nu、NIH-Ⅲ、IL-4T...