Lavi, E., Gilden, D.H., Highkin, M.K., Weiss, S.R. (1984). MHV-A59 Pathogenesis in Mice. In: Rottier, P.J.M., van der Zeijst, B.A.M., Spaan, W.J.M., Horzinek, M.C. (eds) Molecular Biology and Pathogenesis of Coronaviruses. Advances in Experimental Medicine and Biolo...
MHV.A59的杀灭对数值均≥4,具 备杀灭作用,而新洁尔灭的杀灭对数值则<4,杀灭能力较低,对该病毒的灭活效 果很难达到规范中的要求.结论 过氧乙酸,碘伏以及复方二氯异氰尿酸钠对小鼠肝炎病毒的杀灭效果确实,适用于 对小鼠肝炎病毒的消毒. 【关键词l肝炎病毒,鼠;消毒剂;病毒灭活 【中图分类号】R一33【文献标识...
摘要:目的应用藏茵陈对MHV—A59病毒感染湿热证小鼠模型进行治疗,通过实验初步探讨该药对小鼠病毒性肝炎的 干预机制。方法将32只小鼠随机分为正常组、模型组、阳性组和藏茵陈组。分别在造模前后测定小鼠的肛温和体重, 并在造模后分别用试剂盒测定小鼠血清肝功能两项、小鼠肝匀浆MDA含量和SOD活性,通过HE染色后光镜观察...
MHV-A59 causes a chronic demyelinating disease in mice which is accompanied by persistence of viral genome in white matter. As part of the investigation into the mechanism of viral persistence, infection of glial cells, probable targets for chronic infection, was studied by the use of mixed glia...
Infection of mice with a neurotropic strain of MHV (MHV-A59), a non-neurotropic strain of MHV (MHV-2), and a set of recombinant viruses (kindly provided by Dr. Michael Lai) were used to map genetic determinants of viral neurotropism and demyelination. Following intracerebral (IC) inoculat...
Mouse hepatitis virus strain A59 causes a persistent productive, but nonlytic, infection of cultured glial cells. We have mutants isolated from persistently infected glial cell cultures which have been shown to be fusion-defective due to a histidine to aspartic acid mutation (H716D) near the cle...
MHV-A59 1. The standard strainMHV-A59was used to infect 6 strains of mice(BALB/c,C57,nu/nu,NIH-Ⅲ,IL-4T and IL-10T) in three paths(belly,oral route and nasal instillation). 采用MHV-A59标准毒株通过3种途径(腹腔、滴鼻、灌胃)对6个品系的实验小鼠(BALB/c、C57、nu/nu、NIH-Ⅲ、IL-4T...
Mouse Hepatitis Virus(MHV) 鼠肝炎病毒介绍、检测以及防治 Mouse Hepatitis Virus see the problem, see the impact, and see the solution 制作：天下上等
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Expression of the E1 gene of mouse hepatitis virus (MHV A59) in vivo and in vitro S protein of MHV is involved in a variety of important biological functions in viral pathogenicity.It is able to mediate the attachment of virus to the cel... H Niemann,T Mayer,M Wirth,... - 《Advanc...