von Bonin A, Martin S, Plaga S, Hebbelmann S, Weltzien HU: Puri(R)ed MHC class I molecules present hapten-conjugated peptides to TNP/H-2Kb-speci(R)c T-cell hybridomas. Immunol Lett 35:63±68, 1993von Bonin, A., Martin, S., Plaga, S., Hebbelmann, S., and Welt- zien, H...
are extremely polymorphic. They are the main molecules that present pathogen-derived peptides to T cells, and they also interact with natural killer (NK)-cell receptors. By contrast, non-classical MHC class I molecules (also known as MHC class Ib molecules) are diverse in function and genetic...
DRiP, proteasome, antigen presentation, MHC class IMHC class I molecules present peptides derived from intracellular proteins, enabling immune surveillance by CD8+ T cells and the elimination of virally infected and cancerous cells. It has been argued that the dominant source of MHC class I-...
Classical MHC I molecules present antigenic peptide ligands on infected cells to CD81 T cells, whereas a key function for non-classical MHC I molecules is to mediate inhibitory or activating stimuli in natural killer (NK) cells. The structural diversity of MHC I puts immense pressure on ...
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II...
MHC复合物在这个过程中又起到了重要的作用,因此了解MHC I与MHC II在获得性免疫的学习中十分重要。本文主要根据2016年Kenneth等编写的Present Yourself! By MHC Class I and MHC Class II Molecules翻译而成 天然免疫系统主要依赖模式识别受体发现病原体相关分子模式和损伤相关分子模式感知组织稳态的变化,快速做出相应...
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with...
Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide... States that major histocompatibility complex (MHC) class I molecules present peptides derived from the endogenous protein pool to cytotoxic T lymphocytes, ... Spies,T.,Cerundolo,... - 《Nature》 被引...
Class I MHC molecules ___. a) activate B cells b)activate cytotoxic T cells c) are found only on antigen-presenting cells (APCs) d) present exogenous antigens Major Histocompatibility Complex: The major histocompatibil...
MHC class I and class II molecules are also first found in the cartilaginous fishes. Moreover, the MHC genes are also polymorphic in sharks, with multiple alleles of class I and class II loci. In ...