MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum an- tigen binding. Nature 353, 134 -139.Germain,R. and Hendrix.,L.R. (1991) MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature,...
1991. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353:134-139.Germain RN and Hendrix LR ( 1991 ) MHC class II structure, ... RN Germain - 《Nature》 被引量: 257发表: 1991年 MHC class II structure, occupancy and...
Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab Lymphocyte activation gene-3 (LAG3) is an immune checkpoint protein recently approved as a target for anti-melanoma therapy. Here, the authors solve the structure of mouse LAG3 bound to MHC-II to show that ...
TheMHC class Imolecule is aheterodimercomposed of a heavy chain of about 350amino acids, which is encoded within the MHC locus, and a light chain of about 100 amino acids, β2microglobulin, which is encoded elsewhere. The structure of an MHC class I molecule is shown schematically inFig. ...
Differential transmembrane domain GxxxG motif pairing impacts MHC class II structure : Differential transmembrane domain GXXXG motif pairing impacts major histocompatibility complex (MHC) class II structure. J Biol Chem. 2014; 289 ( 17 ):... AM Dixon,L Drake,KT Hughes,... - 《Journal of Biolo...
MHC class II complexes sample intermediate states along the peptide exchange pathway Marek Wieczorek, Jana Sticht, Sebastian Stolzenberg, Sebastian Günther, Christoph Wehmeyer, Zeina El Habre, Miguel Álvaro-Benito, Frank Noé & Christian Freund Nature Communications volume 7, Article nu...
Germain RN, Hendrix LR: MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353: 134–... RN Germain,LR Hendrix - 《Nature》 被引量: 858发表: 1991年 MHC class II structure, occupancy and surface expression determined by post...
CD4+ helper T cells contribute important functions to the immune response during pathogen infection and tumor formation by recognizing antigenic peptides presented by class II major histocompatibility complexes (MHC-II). While many computational algorith
Human MHC Class II Antigens: Genetics, Structure and Function Proceedings of the First International Workshop on Monoclonal Antibodies to Human MHC Class II Antigens Disease Markers (special issue) — Volume 2 Edited by H.M. Dick, C.M. Steel and B. Dupont John Wiley and Sons, Chichester ...
Differential transmembrane domain GXXXG motif pairing impacts major histocompatibility complex (MHC) class II structure : Differential transmembrane domain GXXXG motif pairing impacts major histocompatibility complex (MHC) class II structure. J Biol Chem. 2014; 289 ( 17 ):......