Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+-and protein kinase C–dependent pathway. J Neurochem 2005;93(1):232–245. PubMed CAS Google Scholar Harris SL, Cho K, Bashir ZI, et al. ...
C1GalT1 suppression in SW620 (c) and HCT116F3 (h) cells leads to reduction of cell proliferation and colony formation of SW620 (d) and HCT116F3 (i) cells. The bar charts show average number of colonies with >80 cells. C1GalT1 suppression reduces adhesion of SW620 (e) and HCT116F3...
de Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, et al. LSP2–9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats. Neurosci Lett. 2020. https://doi.org/10.1016/j.neul...
Briefly, recombinant hMGL (100 ng/sample) was pre-incubated for 10 min at 37 °C in 50 mM Tris-HCl buffer [pH 8.0] containing 0.5 mg/ml fatty acid-free BSA w((1ei)0th01 0μ( aMm)M)1w0H0a sm2OthM2e +nD 2aTd0T dm;eMd(ba)Dn2dM0i mDnc...
Trademark HEYI Origin China HS Code 8504311000 Production Capacity 2000PCS/Month Product Description HY 122-30M-LE split core current transformer The KCT range of split core current transformers have been specifically designed to be small CT and easy to open...
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125I-radiolabelled NPY (IM 170, Amersham) was used as a tracer. Assays were carried out in duplicate in polypropylene tubes. Each tube contained a 100 μl aliquot of a diluted sample or the standard and 100 μl of diluted NPY antiserum. After a 48 h preincubation (4°C), 100 μl ...
was co-administered during cocaine (30 mg/ kg, i.p.) or morphine (3.0 mg/kg, s.c.) pretreatment and psychomotor sensitization was tested 3 weeks post-treatment. Results MTEP attenuated the development of morphine- but not cocaine-induced CPP. In contrast, MTEP sup- pressed the development...