A simplified mGlu receptor dimer activation model and its domains: VFD - Venus Flytrap Domain; CRD - cysteine-rich domain; 7TMD - transmembrane heptahelical domain, shown as a cylinder with three highlighted transmembrane helices (TM 4–6) within the lipid bilayer and the intracellular C-terminus...
van Vliet SJ, Bay S, Vuist IM, Kalay H, Garcia-Vallejo JJ, Leclerc C, et al. MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-alpha secretion. J Leukoc Biol. 2013;94:315–23. Article PubMed Google Scholar Robey RW, Pluchino KM, Hall MD, Fojo AT, Bates...
c To find out the role of mGlu8 in the expression of morphine -induced CPP, the animals received highest dose of S-3,4-DCPG (3 μg/0.5 μL saline) or Saline 5 min prior to CPP test Full size image Pre-conditioning phase On day 1, each rat was separately placed in the apparatus...
Alex Pettee is President and Director of Research and ETFs at Hoya Capital. Hoya manages institutional and individual portfolios of publicly traded real estate securities. Alex leads the investing group iREIT®+HOYA Capital. The service features a team of analys...