Cell counts for a region are based on cell counts from a single brain section from each mouse from each treatment group. There was no significant variation of total number of 5-HT-positive cells within each treatment group. Colocalization of c-Fos immunoreactivity with 5-HT in the cell ...
A simplified mGlu receptor dimer activation model and its domains: VFD - Venus Flytrap Domain; CRD - cysteine-rich domain; 7TMD - transmembrane heptahelical domain, shown as a cylinder with three highlighted transmembrane helices (TM 4–6) within the lipid bilayer and the intracellular C-terminus...
The title compound (27 mg, 0.10 mmol) was prepared from 4-chloro-6-(1H-pyrazol-1-yl)pyrimidine (Intermediate 34, 225 mg, 1.25 mmol) and (3-cyano-5-methylphenyl)boronic acid (Intermediate 26, 200 mg, 1.24 mmol) at 90° C. using the methods of Example 2, 3-chloro-5-[6-(pyridin...
Alex Pettee is President and Director of Research and ETFs at Hoya Capital. Hoya manages institutional and individual portfolios of publicly traded real estate securities. Alex leads the investing group iREIT®+HOYA Capital. The service features a team of analys...
THP-1 cells were seeded into 24-well plate (4 × 105cells/well) and differentiated into M1 macrophages as described above. The macrophages were labelled with 8 µl DiO for 40 min at 37 °C. Cancer cells were released by trypsin and washed by PBS and labelled (5 × ...