This study compared the bioavailability of [6S]-5-MTHF with that of folic acid (FA) by measuring plasma folate responses after a single ingestion of equivalent doses of the two folate forms. In a double-blind, crossover study, 13 men (presaturated with FA) received in random order each ...
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methyltetrahydrofolate (L-5-MTHF; 1 mg) vs folic acid (1 mg) vs placebo in a double-blind placebo-controlled study and to compare the relative responsiveness of these patients to L-5-MTHF and folic acid.Patients were recruited from Hepatology-Transplantation-Unit at Johann Wolfgang Goethe-...
In vitro assay showed 5-MTHF's superior inhibitory activity on alpha-amylase compared to folic acid. The protective effect ofSpirulinaaqueous extract and 5-MTHF were validated in vivo using an STZ-induced diabetic Wistar rat model. Supplementation withSpirulinaextract through diet, and a higher ...
Biologically active natural folate form L-5-methyltetrahydrofolate is less stable than synthetic folate form folic acid commonly used for food fortification. The production of electrosprayed capsules using a combination of carbohydrates such as glucose syrup and pullulan was investigated to provide higher...
High performance liquid chromatographic method to determine natural folate (5-methyltetrahydrofolate) and added folic acid content in food matrices.5-Methyltetrahyrofolate (5-MeTHF) was analyzed in food samples using reverse phase chromatography, a gradient mobile phase of 33 mM phosphate buffer (pH...
FOLIC acidRADIOISOTOPESKIDNEY tumorsTUMOR growthSURVIVAL analysis (Biometry)NUCLEAR medicinePurpose: The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a n...
However, the effect of the active forms of folic acid [folinic acid or 5-methyltetrahydrofolate (5-MTHF)] on endothelial health in subjects with ESRD has not been as well-studied =-=[9]-=-. The purpose of the present study was: (i) to examine the direct vascular effect of intra-...