Marc CohenYves J. R. MenezoSpringer USJournal of Assisted Reproduction and GeneticsServy EJ, Jacquesson-Fournols L, Cohen M, et al. MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series [J]. J Ass Reprod Gen, 2018, (35)...
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The Short-term Bioavailabilities of [6S]-5-Methyltetrahydrofolate and Folic Acid Are Equivalent in Men. J. Nutr. 2004, 134, 580-585.Pentieva K, McNulty H, Reichert R, et al. The short-term bioavail- abilities of [6S]-5-methyltetrahydrofolate and folic acid are...
This study compared the bioavailability of [6S]-5-MTHF with that of folic acid (FA) by measuring plasma folate responses after a single ingestion of equivalent doses of the two folate forms. In a double-blind, crossover study, 13 men (presaturated with FA) received in random order each ...
The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent and to compare their properties with those of the previously established folic acid-based [Lu-177]Lu-OxFol-1. Methods [Lu-177]Lu-6R-RedFol...
High performance liquid chromatographic method to determine natural folate (5-methyltetrahydrofolate) and added folic acid content in food matrices.5-Methyltetrahyrofolate (5-MeTHF) was analyzed in food samples using reverse phase chromatography, a gradient mobile phase of 33 mM phosphate buffer (pH...
In patients with chronic renal failure, the administration of folic acid or its metabolites reduces but does not normalize plasma homocysteine concentrations. Furthermore, homocysteine induces endothelial dysfunction by an increased inactivation of nitric oxide.Methods. We examined the effect of the ...
Biologically active natural folate form L-5-methyltetrahydrofolate is less stable than synthetic folate form folic acid commonly used for food fortification. The production of electrosprayed capsules using a combination of carbohydrates such as glucose syrup and pullulan was investigated to provide higher...
5-MTHF, and group B was treated with 5 mg/day oral folic acid. Both groups received i.v. vitamin B6 and B12. By dividing patients into C-reactive protein (CRP) quartiles, group A had the highest survival for CRP <12 mg/l, whereas no survival difference was found for group B. CRP...
et al.The folic acid metabolite L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients:a double-blind placebo-controlled study. European Journal of Clinical Nutrition . 2007B Akoglu, M Schrott, H Bolouri, A Jaffari, E Kutschera, W F...