Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type. BMC Genomics. 2014;15:145.Smith AK, Kilaru V, Kocak M, Almli LM, Mercer KB, Ressler KJ, Tylavsky FA, Conneely KN. Methylation quantitative trait loci (meQTLs) are...
MethylationWe identified genotype variations associated with DNA methylation in the cord blood obtained from Koreans.doi:10.1007/s13273-019-00068-3Jaehyun ParkSung Ok KwonSan-Ha KimSeung Jun KimEun Jung KohSungho WonWoo Jin KimSeung Yong HwangSpringer SingaporeMolecular & Cellular Toxicology...
Genome-wide association studies (GWAS) have recently identified genetic loci associated with site-specific DNAm of CpGs, known as DNA methylation quantitative trait loci (meQTLs)10,11,12,13,14. We hypothesized that identifying meQTL variants and linking them to disease-associated genetic variants f...
(Fig.2B and Additional file2: Table S2). Notably, only 93 of these memo-eQTLs were detected as eQTLs for the corresponding genes, and 81 as methylation quantitative trait loci (meQTLs) associated with matched meCpGs, all withp-values less than 0.05 (Additional file2: Table S2). For ...
Methylation quantitative trait loci (MeQTLs) analysis was performed using a linear model with R package MatrixEQTL67. In total, 433 participants had matched genotype and DNA methylation data that were included in the MeQTL analysis. Mediation analysis was performed with R package Mediation68. Detail...
Quantitative Trait Loci Associated with Drought Tolerance at Reproductive Stage in Rice Drought is a major constraint to rice (Oryza sativa) yield and its stability in rainfed and poorly irrigated environments. Identifying genomic regions infl... Lanceras,C J. - 《Plant Physiology》 被引量: 635...
Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they have not been fully characterized in East Asians (EAs). Here we identified mQTLs in whole blood from 3,523 Chinese individuals and replicated them in...
Abstract Methylation quantitative trait loci (meQTLs) quantify the effects of genetic variants on DNA methylation levels. However, most published studies utilize bulk methylation datasets composed of different cell types and limit our understanding of cell-type-specific methylation regulation. We propose ...
Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type. BMC Genomics. 2014;15:145. Article PubMed PubMed Central Google Scholar Zhang D, et al. Genetic control of individual differences in gene-specific methylation in human ...
Individual genotypes at specific loci can result in different patterns of DNA methylation. These methylation quantitative trait loci (meQTLs) influence methylation across extended genomic regions and may underlie direct SNP associations or gene-environment interactions. We hypothesized that the detection of...