Institute of Hematology and Transfusion MedicineElżbieta Graczyk-PolInstitute of Hematology and Transfusion MedicineSpringer Berlin HeidelbergNowak J, Mika-Witkowska R, Graczyk-Pol E. Genetic methods of HLA typing, in Molecular Aspects of Hematologic Malignancies., Vol. 21. Berlin Heidelberg: Springer-...
The present report reviews current NGS approaches to capture, sequence and analyze HLA genes and loci. The impact of these new methodologies on various applications including HLA typing, population genetics and disease association studies are discussed. 展开 关键词: NGS HLA HLA typing Population ...
Object of the present invention is to provide a highly accurate DNA typing methods and kits, which eliminates the phase ambiguity caused by uncertainty. 本发明提供了HLA的DNA分型方法,其特征为包含以下步骤:(1)制备对人基因组碱基序列中HLAA,HLAB,HLAC,HLADQA1,HLADQB1,HLADPA1和HLADPB1各基因的上游...
Software is used to assign positive or negative reactions based on the strength of the fluorescent signal. The assignment of the HLA typing is based on positive and negative probe reactions compared with published HLA gene sequences. Recently kits characterized by an extensive number of probes/...
HLA-E typing of more than 2.5 million potential hematopoietic stem cell donors: Methods and population-specific allele frequenciesHLA-EAllele frequency distributionsPopulation geneticsUnrelated haematopoietic stem celltransplantationDonor registryMILLION SAMPLES WORKFLOW...
An HLA typing consists of a set of ambiguous genotypes at each locus, and different typing methods generate typings of differing resol... Paunic, Vanja,Gragert, Loren,Madbouly, Abeer,... - 《Tissue Antigens》 被引量: 0发表: 2012年 A haplotype of β2-adrenoceptor is associated with the ...
reading step, which may readily be automated, is achieved. The methods may be particularly suitable for use with ARMS-PCR methods for SNP typing, in particular HLA typing. The method may be useful for identifying numerous sequence polymorphisms, such as those within the DR locus of HLA Class ...
Accordingly, there remains a need in the art for improved methods of HLA typing including methods for determination of percentage of PRA which is rapid, convenient and accurate.SUMMARYIn one aspect, described herein is a composition comprising a first collection of solid-phase substrates each coated...
Methods: We studied the histocompatibility antigen genes, HLA-A, B, C, DRB1, and DQB1, of 71 ... M Ueta,K Tokunaga,C Sotozono,... 被引量: 5发表: 2013年 Discrepancies in HLA typing: use of different methods to confirm doubtful or inconclusive results http://dx.doi.org/10.4025/...
Methods for HLA typing are described, including serological methods, molecular techniques of sequence-specific priming (SSP), sequence-specific oligonucleotide ... BM Mahdi - 《Clinical & Translational Medicine》 被引量: 40发表: 2013年 Impact of molecular histocompatibility typing on outcome of unrelate...