Collectively, these findings underscore a burgeoning interest in this area and advancements in understanding the role of protein acetylation in bacteria as the principal posttranslational modification. This und
Protein complex composition identifies genes that function together and provides clues about regulation within and between cellular pathways. Cytosolic protein complexes control metabolic flux, signal transduction, protein abundance, and the activities of cytoskeletal and endomembrane systems. It has been ...
While aiding the design of selective binders, the low abundance of cysteine also presents a problem and excludes many potential targets. In the case of 14-3-3 proteins, the different isoforms are highly similar in sequence and there is some degree of functional redundancy in their activity56,57...
While efficient methods are well established for studying postsynaptic protein regulation of glutamatergic synapses in the mammalian central nervous system, similarly efficient methods are lacking for studying proteins regulating presynaptic function. In the present study, we introduce an optical/electrophysiolog...
Both the HKA and MK tests use the chi-squared test or Fisher exact test to evaluate the fit of data to the null hypothesis of neutrality. The chi-squared test has limited power and provides no insights into the selective process without inferring parameters. Multiple methods were proposed to ...
When RNA was extracted from Lilium leaf using the Kit and CTAB methods, the spectrophotometric results showed that the A260/A230 ratios of RNA ranged from 0.91 to 1.07, and the A260/A280 ratios ranged from 1.69 to 2.01, indicating that the RNA samples were contaminated by proteins, ...
The penetration of substances from the surface to deep inside plant tissues is called infiltration. Although various plant tissues may be effectively saturated with externally applied fluid, most described infiltration strategies have been developed for
Single-cell multimodal sequencing technologies are developed to simultaneously profile different modalities of data in the same cell. It provides a unique opportunity to jointly analyze multimodal data at the single-cell level for the identification of distinct cell types. A correct clustering result is...
to find proteins significantly altered in thermal stability—and thus potential ligand interactors—via anF-statistic (example fits for the null and alternative model are shown in Supplementary Fig.1). Theq–qplot on the right compares bootstrapped and observedF-statistics. Although the majority of ...
et al., “Up-Regulation of Somatostatin Receptor Subtype 2 (SST-2) mRNA Occurs During the Transformation of Human Endothelium to the Angiogenic Phenotype,” Paper Presented at the 12th International Symposium on Regulatory Peptides, Copenhagen, Denmark, Sep. 1996. Welshons, W.V. et al., “...