Metformin and vitamin B12deficiency:the role of H2receptor antagonists and proton pump inhibitors. Varughese GI,Scarpello JH. Age and Ageing . 2007Metformin and vitamin B12 deficiency: the role of H2 receptor antagonists and proton pump inhibitors. Varughese George I,Scarpello John H B. Age and...
The majority of the women had not had their B12levels measured. However, upon testing, almost 1 in 10 were found to have a B12deficiency. Although metformin is recommended for the first-line treatment of type 2 diabetes, it is associated with vitamin B12deficiency, which itself increases the ...
Association of biochemical [B.sub.12] deficiency with metformin therapy and vitamin [B.sub.12] supplements: the National Health and Nutrition Examination Survey, 1999-2006 To describe the prevalence of biochemical B(12) deficiency in adults with type 2 diabetes taking metformin compared with those...
Vitamin B12deficiency is estimated to be present in up to 30% of patients with diabetes taking metformin.[1]The risk for vitamin B12deficiency increases with patient age and the dose and duration of metformin use.[5,7]Concomitant conditions such as suboptimal dietary intake, which is common amo...
3) Metformin is known to increase homocysteine,a key driver of histone formation in cancer and other chronic illnesses. It is also known to increase the risk of neuropathy (23). 4) Metformin has also been shown to cause vitamin B-12 deficiency(24). In research, this was linked to the ...
Vitamin B12 deficiency is an easily preventable side effect of metformin therapy. It is essential to determine the prevalence of this condition in order to prevent the occurrence of complications, such as peripheral neuropathy and ... O Marar,S Senturk,A Agha,... 被引量: 12发表: 2011年 Per...
Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus. ObjectivesMetformin is widely used in patients with type 2 diabetes but may decrease vitamin B levels and increase levels of homocysteine (Hcy), a cardio...
Oral manifestations of vitamin B12 deficiency Six cases of vitamin B 12 deficiency presenting with a sore tongue are described. Only one of these had significant changes in the peripheral blood. The value of an assay of the serum vitamin B 12 is discussed. JM Faccini - 《British Journal of ...
Malabsorption of vitamin B 12 and intrinsic factor secretion during biguanide therapy In a survey of 46 randomly selected diabetic patients on biguanide therapy, 30% had malabsorption of vitamin B 12 . Withdrawal of the drug resulted in norm... JF Adams,JS Clark,JT Ireland,... - 《Diabetologi...
Decreased serum vitamin B12 concentrations, with or without clinical manifestations (e.g., anemia).Symptoms rapidly reversible following discontinuation of metformin or supplementation with vitamin B12. Monitor hematologic parameters (e.g., hemoglobin, serum vitamin B12 concentrations) prior to initiation ...