For example, in breast cancer, IL6 is secreted by differentiated cancer cells to support CSC survival and self-renewal5. Differentiated glioblastoma cells have also been reported to promote glioma stem cell self
Testicular tumor, as the most common tumor in young men, is associated with a 5 year survival rate close to 100% in early stages. Pure seminoma are the most frequent histological subtype (55%) nowadays and more than 70% of patients present without visible metastasis at primary staging [1]...
The 5-year survival rate for oral cavity cancer is poorer than for breast, colon or prostate cancer, and has improved only slightly in the last three decades. Hence, new therapeutic strategies are urgently needed. Here we demonstrate by tissue micro array analysis for the first time that RNA...
Astrocytes have been shown to produce a wide variety of cytokines and growth factors; among them, it was suggested that IL-6, TNF-α and IL-1β may contribute to the development of brain metastasis by lung cancer cells [8], and IL-6, TGF-β and IGF-1 by breast cancer cells [9]....