Globally, cancer stands as the predominant cause of mortality, with the World Health Organization attributing over 90% of cancer-related deaths to metastasis. Annually, ~18 million individuals receive a cancer diagnosis, and of these, an estimated 10–15% will manifest metastases. Prevalent cancers ...
Globally, cancer stands as the predominant cause of mortality, with the World Health Organization attributing over 90% of cancer-related deaths to metastasis. Annually, ~18 million individuals receive a cancer diagnosis, and of these, an estimated 10–15% will manifest metastases. Prevalent cancers ...
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In particular, cuproptosis can act as the immunogenic cell death (ICD) evoker to release damage-associated molecular patterns (DAMPs), and then improve tumor immunogenicity24,25. Despite the fact that cuproptosis combined with immunotherapy have shown some benefit for lung metastasis, cuproptosis-...
Cell adhesion molecule CD166/ALCAM functions within the crypt to orchestrate murine intestinal stem cell homeostasis. Cellular and Molecular Gastroenterology and Hepatology, 3(3), 389–409. https://doi.org/10.1016/j.jcmgh.2016.12.010. Article PubMed PubMed Central Google Scholar Jung, P., ...
[10]. The viruses are sourced from naturally occurring viruses in the environment and selected based on their innate ability to induce immunogenic cell death (ICD) in cancer cells, with their tumor selectivity enhanced through genetic engineering or specific viral vectors to promote replication, ...
differences in disease outcomes.Methods:A retrospective analysis of National Inpatient Sample (NIS) data from 2016 to 2020 was conducted, identifying adults with HCC using International Classification of Diseases, Tenth Revision (ICD-10) codes, and categorizing them based on the presence of metastasis...
Bone is the first most common site of distant FTC metastases and the second most frequent site of PTC metastases [10]. Bone FTC metastases most commonly occur in long bones such as the femur and flat bones such as the iliac bone and sternum, whereas PTC most commonly metastasizes to the ...
Primary tumors may create the premetastatic niche in secondary organs for subsequent metastasis. Humoral immunity contributes to the progression of certain cancers, but the roles of B cells and their derived antibodies in premetastatic niche formation are poorly defined. Using a mouse model of spontan...
Bone is the most common site of metastasis, and although low proliferation and immunoediting at the early stage make existing treatment modalities less effective, the microenvironment-inducing behaviour could be a target for early intervention. Here we r