The CXCR4/CXCL12 axis also has a relevant role in experimental models of metastasis (Stamatovic et al, 2005; Wang et al, 2010) and is supposed to be crucial in brain metastases formation from breast cancer. CXCR4 and its ligand, CXCL12, are expressed in astrocytes, microglia, neurons and...
~18 million individuals receive a cancer diagnosis, and of these, an estimated 10–15% will manifest metastases. Prevalent cancers encompass those of the breast, lung, colon, rectum, and prostate. From 1991 to 2019
Oncolytic virotherapy (OVT) is a promising emerging cancer immunotherapy that leverages the natural ability of certain replicating viruses to infect and preferentially lyse tumor cells while leaving non-tumor cells intact [10]. The viruses are sourced from naturally occurring viruses in the environment ...
Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA Breast Cancer Res, 25 (2023), p. 59 CrossrefGoogle Scholar 7 M.M. Wu, Y.F. Liang, X. Zhang Changes in pulmonary microenvironment aids lung metastasis of breast...
We previously showed that HSD17B14 overexpression in ER+ breast cancer models leads to high intracellular E1 and is pro-inflammatory and pro-oncogenic.24 Here, we investigated the associations between HSD17B enzymes and metastasis. Analysis of breast cancers from The Cancer Genome Atlas (TCGA) ...
For breast, lung and colon cancers, the prevalence of brain metastasis ranged from 4-10% in patients with the lowest risk scores to 92-100% in patients with the highest however the distribution of cases with each risk score was markedly different across cancer type. Breast cancer had 62% ...
MiR-487a promotes TGF-beta1-induced EMT, the Migration and Invasion of breast Cancer cells by directly targeting MAGI2. Int J Biol Sci. 2016;12(4):397–408. 23. Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY. miRNA-487a promotes proliferation and metastasis in Hepatocellular ...
W. (2012). Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells. International Journal of Oncology, 40(1), 130–138. https://doi.org/10.3892/ijo.2011.1193. Article CAS PubMed Google Scholar Record, M., Poirot, M., & ...
This study aimed to evaluate the diagnostic performance of a non-radiating, noninvasive infrared (IR) thermal imaging system in the detection of cervical lymph node metastasis from oral cavity cancer. In this prospective clinical trial, a total of 90 oral cavity cancer patients suspected of having...
The GWAS data for prostate cancer were sourced from FinnGen Release 10 (https://www.finngen.fi/en)33, which was published in December 2023. Prostate cancer in FinnGen was defined based on the International Classification of Disease (ICD), encompassing 15,199 cases, and 131,266 controls. Me...