Triple negative breast cancerImmunogenic cell deathImmunoadjuvantα5β1-targeted micellar paclitaxel (ATN-MPTX) shows high selectivity and strong ICD in murine 4T1 cells.ATN-MPTX diaplays superior inhibition of metastatic 4T1 tumor to free PTX and MPTX.ATN-MPTX plus nano-STING agonist augments ...
While this new coding system has advantages for clinical care and billing, the degree to which providers are utilizing the expanded code structure is unknown. The study objective was to describe the use of ICD-10 vision codes in a large cohort of stroke survivors. We used a retrospective ...
Recently, γ-secretase inhibitors aimed at blocking Notch receptor cleavage, including PF-03084014, MK-0752, and RO4929097, have been administered in clinical studies to treat locally advanced or metastatic pancreatic cancer; however, no significant remission has been observed13,14,15. Dual- or pan...
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309PEfficacy and toxicity of endocrine therapy + cyclin-dependent kinases 4/6 inhibitors (iCDK4/6) in metastatic breast cancer patients according to gBRCA statusdoi:10.1093/annonc/mdy272.299Bruno, L ICostanzo, M VOstinelli, C ANervo, A A...
We investigated the p75 Neurotrophin Receptor (p75NTR) expression and cleavage product p75NTR Intracellular Domain (p75ICD) as potential oncogenic and metastatic markers in human Laryngeal Squamous Cell Carcinoma (LSCC). p75NTR is highly expressed in Cancer Stem Cells (CSCs) of the laryngeal epithelia...