In recent years, the metal phenolic network (MPN) based on polyphenol metal coordination has been recognized in a variety of biomedical functional materials due to its excellent properties. Polyphenols as an ex
Metal-phenolic network nanoparticles have been proposed as a promising strategy for cancer therapy. In this work, eight-arm PEG succinimidyl glutarate, copper ions and doxorubicin (DOX) were integrated into one nanoparticle via hydrophobic interactions and coordination interactions to achieve chemotherapy ...
Assembly of nanostructured interfaces on biomaterials is proven to be an effective way for manipulating cell behavior to facilitate tissue regeneration14. Metal phenolic network (MPN), a complex supramolecular structure formed by the coordination of metal ions and phenolic ligands, has been widely studie...
anti-cancer, and anti-aging effects. Studies by Gao has found that quercetin can mitigate acute kidney injury by inhibiting ferroptosis through the reduction of malondialdehyde and lipid reactive oxygen levels [48]. In cancer therapy, quercetin has been reported to promote...
setting huge obstacles for further industrialization of this technology. Herein, a metal–phenolic network (MPN)-engineered 2D cotton fabric anchored with redox graphene oxide (rGO) is reported, where the MPN coatings afford the engineering of photothermal fabric cottons with high heating efficiency and...
delivery at a precise point, sensors, pharmaceuticals to combat cancer, antioxidants, larvicides, Nanofluids, antibacterial agents in dentistry, mouthwashes, the treatment of white spot lesions during orthodontic therapy, and more. Since the size reduction limits the electron movements, NPs have ...
(2) metal–phenolic coordination that affords NPs with a rich choice of building blocks and chemical diversity; and (3) a seeding agent that can increase the local concentrations of precursors (mRNA and polyphenols) and drive the formation of NPs under ambient conditions. The engineered mRNA-MPN...
With a relatively high content of active phenolic hydroxyl groups, MOPS assemblies possess many physicochemical properties that are similar to NPPs, including metal chelation and affinity for different materials. These polyphenolic properties, based on polyphenol chemistry, enabled the NPPs to be utilized...
3.1.2. Copper-based MPNs are used for chemokinetic therapy CDT as a new cancer treatment strategy, combined with the TME (low oxygen content, high concentration of ROS, low pH, and redox environment) [82] and transition metal (such as Fe, Cu, Mn, Co, and Ni) some unique inherent pro...
alone, or in combination, with other therapeutic agents, including anti-cancer agents, such as cisplatin or gemcitabine. The pharmacologic agents can be used as an adjuvant, before, after, or concurrent with the administration of other medications or treatment therapies, such as radiation therapy. ...