Metal-phenolic networks-encapsulated cascade amplification delivery nanoparticles overcoming cancer drug resistance via combined starvation/chemodynamic/chemo therapyMetal-phenolic networksCancer drug resistanceProdrugStarvation therapyChemodynamic therapyCombination therapy...
effectively suppressing the expression of P-gp and sensitizing cancer cells to DOX.The inhibition of COX-2 pathway can elicit an upregulation in intracellular arachidonic acid concentration, thereby enhancing Fe3+-induced ferroptosis.The nanosystem demonstrated excellent photothermal performance, promoting ...
To determine the mRNA loading capacity of mRNA-MPN NPs, the mixture of PEG, mRNA, phenolic ligand, and metal ion was diluted with RNase-free water and loaded on 1% agarose gels with a concentration of 200 ng mRNA per well. Note that the uncropped unprocessed gel scan for the inset of...
Metal-phenolic networks (MPNs) are multifunctional hybrid nanomaterial nanoplatforms formed by the coordination of metal ions with polyphenols, and they have the potential for wide-ranging medicinal applications. AuAg@PC-Fe NPs, also known as branched AuAg NPs, were thus stuffed with MPNs. In addi...
phenolic compounds (e.g. phenol, biphenol A, 2,4-dichlorophenol), and wastewater decolorization (Alvarado-Ramírez et al.2024; Liang et al.2022). MOFs exhibiting peroxidase-like activity are also eagerly used. In this case, the main application is to use such biomimetic catalysts for sensing ...
MOPS-based metal–phenolic network (MPN) core–shell particle and capsule assembly All solutions were freshly prepared. In a typical synthesis, 300 µL of polystyrene (PS) particles (2.5 wt.% in water) was first added to 570 µL of water. Then, 30 µL of FeCl3 solution (...
conditions. The luminescent, catalytic, and molecular recognition properties of these coordination materials are described with representative recent examples. Their applications ranging from biosensing, enzyme encapsulation, catalysis, templated shell growth to cancer therapy are highlighted. Finally, challenges...
Metal-phenolic networks Antibacterial coating Silver Anti-inflammatory Malate-based polymer 1. Introduction Infections associated with bacteria and biofilms are a problematic issue, especially in the field of medical implants [1]. Implant-associated infections (IAIs) often lead to medical implant failure ...
setting huge obstacles for further industrialization of this technology. Herein, a metal–phenolic network (MPN)-engineered 2D cotton fabric anchored with redox graphene oxide (rGO) is reported, where the MPN coatings afford the engineering of photothermal fabric cottons with high heating efficiency and...
Metal-phenolic networksCancer drug resistanceProdrugStarvation therapychemodynamic therapyCombination therapyMultidrug resistance (MDR) of cancer is the main reason for cancer chemotherapy failure, and the use of anticancer drugs usually brings about adverse side effecChen, Xiaolu...