Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases[J] . Antonio Uccelli,Alice Laroni,Mark S Freedman.Lancet Neurology . 2011 (7)Uccelli A,Laroni A,Freedman MS.Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases[...
摘要: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system (CNS). In attempt to identify an appropriate treatment for improving the neurolog... 查看全部>>关键词: Multiple sclerosis Demyelination Mesenchymal stem cells Immune system Clinical trials ...
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively expanded in vitro. Although their true in situ properties and biological functions remain to be elucidated, these in vitro expanded cells have been shown to possess pot
Mesenchymal stem cells as a treatment for multiple sclerosis: a focus on experimental animal studies. Rev Neurosci. 2020;31(2):161–79. Article PubMed Google Scholar Cosenza S, Toupet K, Maumus M, Luz-Crawford P, Blanc-Brude O, Jorgensen C, et al. Mesenchymal stem cells-derived ...
Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 3Tumor Immunology and Gene Therapy Center, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200433, China Mesenchymal stem cells (MSCs), ...
Mesenchymal stem cells (MSCs) show great therapeutic potential for the treatment of various immune mediated diseases, including Multiple Sclerosis (MS). Systemic administration of MSCs during experimental allergic encephalomyelitis (EAE), an animal model for MS, was shown to reduce the infiltration of ...
Intrinsic Hemocompatibility and Incompatibility of Stem Cell Types In Vivo Several progenitor cell types with (potential) circulating phenotype are of interest when discussing the hemocompatibility aspects of cellular therapies (Figure 2A): (i) hematopoietic stem cells (HSCs), (ii) endothelial progenitor...
Jun 05, 2024 - Mesenchymal stem cells (MSCs) are adult stem cells with the ability to differentiate into various types of mesoderm-derived cells, showing promising results in preclinical studies for various medical conditions. Research continues to explo
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for over a few decades by virtue of their differentiation capacity, potent immunomodulatory properties, and their ability to be favorably cultured and manipulated. Recen
Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Secondary Progressive Multiple Sclerosis Background: Multiple sclerosis (MS) is an irreversible and demyelinating disease of the brain and spinal cord that causes significant disability in young people. However, therapeutic options to effectiv...