Conclusions Cause-specific survival after meningioma surgery is greater in younger, low-comorbidity adults with spinal and benign meningioma. Those with an intracranial, progressing malignant tumor requiring cerebrospinal fluid shunting and having a severe global health-state have a significant increased ...
The perioperative mortality (OR=0.65 [0.46-0.91], p<0.05) and worsened neurological outcome rate (OR=0.70 [0.60-0.83], p<0.0001) were significantly lower in later decade, but the four surgical periods were similar regarding postoperative infections and hematomas. Retreatment-Free Survival (RFS) ...
Multivariate analysis confirmed that age (<50 years) and total surgical excision were independent prognostic factors for survival. Adjuvant RT reduces tumor recurrence, especially after incomplete surgery. 展开 关键词: Adjuvant radiotherapy Atypical meningioma Prognostic factors ...
The most commonly used, IOMM-Lee, shows a high tumor take rate in subgroup analysis for both orthotopic models 87% (95% CI 95–98%) and heterotopic models 94% (90–96%), and it shows median survival of 10–27 days in orthotopic models, depending on the number of cells. In general...
The actuarial determinate survival rates at 10 years were 49%, 81%, and 93%, respectively. Postoperative radiation therapy was also effective for patients treated at the time of the first recurrence, with an actuarial local control rate at 10 years after salvage treatment of 30% for patients ...
The patient was transferred to our neurosurgical department and afterwards surgery was performed with gross total removal of the tumoral mass. Histological examination revealed atypical meningioma with direct invasion into the adjacent brain parenchyma. A week later she was discharged from the hospital in...
Progression free survival of chordoid, otherwise grade 1 meningioma was comparable to non-chordoid WHO grade 1 meningioma (p = 0.75), and significantly better than chordoid WHO grade 2 meningioma (p = 0.019). Conclusion: the chordoid histology alone may not justify a universal WHO ...
We next retrospectively sought follow-up survival data from the time of first surgery, which was available for 25 of the 28 patients included in the transcriptome analysis (12 patients in C1, 13 in C2; mean follow-up of 1,403 days from surgery). We observed a significantly worse overall ...
On multivariate analysis age >60 years (p = 0.001) and high mitotic rate (p = 0.02) remained significant adverse prognostic factors. The 5- and 10-year disease-free survival rates were 58% and 48%, respectively, and were significantly influenced by KPS (p = 0.04) and high mitotic rate ...
CTSD, or Cathepsin D, in particular is associated with caspase-3 induction of cell death and its downregulation may be related to schwannoma cell survival (Pranjol et al., 2015). In order to identify proteins that were highly activated we wanted to identify those that displayed a relatively ...