Medshine Discovery Inc. has divulged azaspiro compounds acting as leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of Parkinson’s disease.
Chen, Shuhui (Shanghai, CN) Application Number: 17/790985 Publication Date: 03/30/2023 Filing Date: 01/07/2021 Export Citation: Click for automatic bibliography generation Assignee: MEDSHINE DISCOVERY INC. (Nanjing, Jiangsu, CN) International Classes: ...
Assignee: MEDSHINE DISCOVERY INC. (Nanjing, Jiangsu, CN) International Classes: A61K31/437; A61K31/4725; A61K31/55; C07D401/12; C07D471/04; C07D487/04 Field of Search: 514/307, 514/300, 546/139, 546/113 View Patent Images: Download PDF 9856264 US Patent References: 8415372 ...
Provided are a compound represented by formula (I), an isomer or a pharmaceutically acceptable salt thereof, and an application of the same in preparing a drug for treating a disease related to A2A receptor. The R1, R2, R3, ring A, ring B, n, and m are as defined in the specification...
Assignee: MEDSHINE DISCOVERY INC. (Nanjing, Jiangsu, CN) International Classes: A61K47/68; C07K16/28; C07K16/30; C07K19/00 Field of Search: 548/545 View Patent Images: Download PDF 10280229 US Patent References: 8163888 Method of targeting specific cell populations using cell-binding agent...
Assignee: MEDSHINE DISCOVERY INC. (Jiangsu, CN) International Classes: C07D471/04; A61K31/7048; A61P35/00; C07D471/20; C07D491/20 Field of Search: 514/278 View Patent Images: Download PDF 11230549 US Patent References: 20210198257 IMIDAZOLONYLQUINOLINES AND THE USE THEREOF AS ATM KINASE...
The present invention discloses a benzimidazole-linked indole compound acting as novel divalent IAP antagonist, specifically disclosing the compound shown in formulas (I) or a pharm