LI, Jian (Shanghai, CN) Chen, Shuhui (Shanghai, CN) Application Number: 17/790985 Publication Date: 03/30/2023 Filing Date: 01/07/2021 Export Citation: Click for automatic bibliography generation Assignee: MEDSHINE DISCOVERY INC. (Nanjing, Jiangsu, CN) ...
Provided are a compound represented by formula (I), an isomer or a pharmaceutically acceptable salt thereof, and an application of the same in preparing a drug for treating a disease related to A2A receptor. The R1, R2, R3, ring A, ring B, n, and m are as defined in the specification...
Due to the limited access to healthcare service and the level of awareness of the disease in China rural areas, the ultra early thrombolysis treatment cannot be achieved for most patients. For patients beyond the thrombolysis window, there are limited medical treatment options to reduce further ...
Disclosed are a series of quinolino-pyrrolidin-2-one compounds, and application thereof in preparation of drugs for ATM inhibitor-related diseases. The present disclosure specifical
The present invention relates to linkers, containing amide surrogates with a regular or a novel lysosomal enzymatic cleavable dipeptidic unit, to connect cytotoxic drugs to antibodies. The present invention also relates to ADCs (antibody-drug conjugates) derived from these amide surrogate linkers for ...
The present invention discloses a benzimidazole-linked indole compound acting as novel divalent IAP antagonist, specifically disclosing the compound shown in formulas (I) or a pharm