The invention relates to a pharmaceutical composition for treating polycystic kidney disease. The active ingredients of the pharmaceutical composition comprise effective doses of thiazolidinediones and diuretics. The preferential combination is as follows: the thiazolidinediones are selected from rosiglitazone ...
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease During kidney organogenesis, tubular epithelial cells proliferate until a functional tubule is formed as sensed by cilia bending in response to fluid flow... SJ Leuenroth,D Okuhara,JD Shotwell,... - 《Proceedi...
Polycystic kidney disease (PKD) is a heritable disorder with diffuse cystic involvement of both kidneys without other dysplastic elements. The term PKD is generally used to describe two genetically distinct syndromes: Autosomal dominant polycystic kidney disease (ADPKD) Saccular, epithelial-lined, fluid...
The prescription patterns of traditional Chinese medicine for women with polycystic ovary syndrome in Taiwan Polycystic ovary syndrome (PCOS) is a common endocrine disease of reproductive-age women, accounting for about 9% to 18% of all women in this age group. Hy... MJ Lin,HW Chen,PH Liu,...
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a prevalent genetic disorder characterized by the formation of renal cysts leading to kidney failure. Despite known genetic underpinnings, the variabilit... Jiayi Lv, Bingxue Lan, Lili Fu, Chaoran He, Wei Zhou, Xi Wang, Chenchen Zhou, Zhigu...
Targeting this pathway using a glucose analog that cannot be metabolized resulted in slower disease progression in mouse models of polycystic kidney disease. This work thus suggests a new potential therapeutic approach for autosomal dominant polycystic kidney disease (pages 488–493). This is a ...
CKD results from a variety of causes, including diabetes, glomerulonephritis, hypertension, infections and polycystic kidney disease [1]. Most forms of CKD are progressive [1,2] and are characterized by disrupted glomerular perm-selectivity [3], glomerular sclerosis, albuminuria, loss of podocytes ...
Autosomal dominant polycystic kidney disease is caused by mutation of PKD1 (polycystic kidney disease-1) or PKD2 (polycystic kidney disease-2). PKD1 and PK... R Sen 被引量: 3发表: 2010年 [Advances in Experimental Medicine and Biology] Transient Receptor Potential Canonical Channels and Brain D...
Somatic mutation in autosomal dominant polycystic kidney disease revealed by deep sequencing human kidney cysts Amali C. Mallawaarachchi Yvonne Hort Mark J. Cowley ArticleOpen Access19 Dec 2024 Efficient reinterpretation of rare disease cases using Exomiser Letizia Vestito Julius O. B. Jacobsen ...
Use of a longitudinal study design allows for more precise analysis of the interplay between clonal hematopoiesis and atherosclerotic disease, finding that whereas clonal hematopoiesis confers an increased risk of atherosclerosis, the reverse is not the case, arguing for a unidirectional effect of clonal...